About   Help   FAQ
Frrs1l Gene Detail
Summary
  • Symbol
    Frrs1l
  • Name
    ferric-chelate reductase 1 like
  • Synonyms
    6430704M03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442704
    NCBI Gene: 230235
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:56957173-56990391 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 31.66 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1026 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442704
 protein coding gene Chr4:56957173-56990408 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028314
 protein coding gene Chr4:55730916-55765667 (-)
A/J MGP_AJ_G0028275
 protein coding gene Chr4:53603970-53638859 (-)
AKR/J MGP_AKRJ_G0028224
 protein coding gene Chr4:55088758-55123037 (-)
BALB/cJ MGP_BALBcJ_G0028294
 protein coding gene Chr4:53754405-53789072 (-)
C3H/HeJ MGP_C3HHeJ_G0028015
 protein coding gene Chr4:55589998-55625479 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028735
 protein coding gene Chr4:57715251-57751320 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026041
 protein coding gene Chr4:50401249-50433889 (-)
CAST/EiJ MGP_CASTEiJ_G0027453
 protein coding gene Chr4:55296588-55333816 (-)
CBA/J MGP_CBAJ_G0027980
 protein coding gene Chr4:59715022-59751842 (-)
DBA/2J MGP_DBA2J_G0028130
 protein coding gene Chr4:53507199-53540819 (-)
FVB/NJ MGP_FVBNJ_G0028097
 protein coding gene Chr4:52716575-52760214 (-)
LP/J MGP_LPJ_G0028229
 protein coding gene Chr4:55833191-55870050 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028121
 protein coding gene Chr4:62865033-62901536 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028771
 protein coding gene Chr4:55258513-55299767 (-)
PWK/PhJ MGP_PWKPhJ_G0027178
 protein coding gene Chr4:53488434-53524919 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027006
 protein coding gene Chr4:54533191-54567956 (-)
WSB/EiJ MGP_WSBEiJ_G0027531
 protein coding gene Chr4:55213584-55248376 (-)



Homology
more
  • Human Ortholog
    FRRS1L, ferric chelate reductase 1 like
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FRRS1L, ferric chelate reductase 1 like
  • Synonyms
    C9orf4, CG-6, CG6, DEE37, EIEE37
  • Links
    NCBI Gene ID: 23732
    neXtProt AC: NX_Q9P0K9
    UniProt: Q9P0K9

  • Chr Location
    9q31.3; chr9:109130293-109167249 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human FRRS1L associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    749
  • Tissues
    23
  • cDNA Data
    17
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000045589 Ensembl Gene Model | MGI Sequence Detail 33219 C57BL/6J ±  kb
    transcript ENSMUST00000053681 Ensembl | MGI Sequence Detail 6817 Not Applicable  
    polypeptide ENSMUSP00000052507 Ensembl | MGI Sequence Detail 293 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17

      Microarray probesets 3
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 4
      Gene Ontology 7
      Phenotypes 14
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory