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Baz2b Gene Detail
Summary
  • Symbol
    Baz2b
  • Name
    bromodomain adjacent to zinc finger domain, 2B
  • Synonyms
    5830435C13Rik, D2Ertd794e
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442782
    NCBI Gene: 407823
  • Alliance
    gene page
  • Transcription Start Sites
    24 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:59729707-60040183 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 34.18 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    7447 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442782
 protein coding gene Chr2:59729707-60040243 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025758
 protein coding gene Chr2:59462754-59790614 (-)
A/J MGP_AJ_G0025734
 protein coding gene Chr2:57163062-57484784 (-)
AKR/J MGP_AKRJ_G0025704
 protein coding gene Chr2:58734966-59053326 (-)
BALB/cJ MGP_BALBcJ_G0025729
 protein coding gene Chr2:57272610-57588693 (-)
C3H/HeJ MGP_C3HHeJ_G0025490
 protein coding gene Chr2:58839947-59168635 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026176
 protein coding gene Chr2:61225161-61553028 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023580
 protein coding gene Chr2:54757298-55072074 (-)
CAST/EiJ MGP_CASTEiJ_G0024954
 protein coding gene Chr2:58876923-59207616 (-)
CBA/J MGP_CBAJ_G0025470
 protein coding gene Chr2:63541287-63896320 (-)
DBA/2J MGP_DBA2J_G0025601
 protein coding gene Chr2:56778448-57087437 (-)
FVB/NJ MGP_FVBNJ_G0025563
 protein coding gene Chr2:56321831-56636746 (-)
LP/J MGP_LPJ_G0025689
 protein coding gene Chr2:59315586-59642689 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025594
 protein coding gene Chr2:65164172-65508735 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026233
 protein coding gene Chr2:58763625-59090063 (-)
PWK/PhJ MGP_PWKPhJ_G0024695
 protein coding gene Chr2:56620601-56938182 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024502
 protein coding gene Chr2:58846695-59161308 (-)
WSB/EiJ MGP_WSBEiJ_G0025022
 protein coding gene Chr2:59060832-59385751 (-)



Homology
more
  • Human Ortholog
    BAZ2B, bromodomain adjacent to zinc finger domain 2B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BAZ2B, bromodomain adjacent to zinc finger domain 2B
  • Synonyms
    WALp4
  • Links
    NCBI Gene ID: 29994
    neXtProt AC: NX_Q9UIF8
    UniProt: Q9UIF8

  • Chr Location
    2q24.2; chr2:159315312-159712442 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 2 alleles in 2 genetic backgrounds
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit increased liver regeneration with less damage.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    775
  • Tissues
    54
  • cDNA Data
    24
  • Literature Summary
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000026987 Ensembl Gene Model | MGI Sequence Detail 310477 C57BL/6J ±  kb
    transcript ENSMUST00000112550 Ensembl | MGI Sequence Detail 7895 Not Applicable  
    polypeptide ENSMUSP00000108169 Ensembl | MGI Sequence Detail 2123 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 25
      cDNA 24
      Primer pair 1

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1289216, MGI:3039620
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 9
      Gene Ontology 5
      Phenotypes 18
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory