About   Help   FAQ
Flad1 Gene Detail
Summary
  • Symbol
    Flad1
  • Name
    flavin adenine dinucleotide synthetase 1
  • Synonyms
    A930017E24Rik, Pp591
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443030
    NCBI Gene: 319945
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:89309980-89319188 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 39.10 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    277 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443030
 protein coding gene Chr3:89308311-89319188 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027437
 protein coding gene Chr3:89613761-89626313 (-)
A/J MGP_AJ_G0027401
 protein coding gene Chr3:86648076-86659949 (-)
AKR/J MGP_AKRJ_G0027365
 protein coding gene Chr3:88740737-88755232 (-)
BALB/cJ MGP_BALBcJ_G0027410
 protein coding gene Chr3:86615211-86626063 (-)
C3H/HeJ MGP_C3HHeJ_G0027152
 protein coding gene Chr3:88947044-88957839 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027856
 protein coding gene Chr3:92999963-93012722 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025208
 protein coding gene Chr3:82131285-82142135 (-)
CAST/EiJ MGP_CASTEiJ_G0026598
 protein coding gene Chr3:89303450-89316750 (-)
CBA/J MGP_CBAJ_G0027126
 protein coding gene Chr3:96188838-96199716 (-)
DBA/2J MGP_DBA2J_G0027264
 protein coding gene Chr3:86026411-86037300 (-)
FVB/NJ MGP_FVBNJ_G0027232
 protein coding gene Chr3:84368926-84380063 (-)
LP/J MGP_LPJ_G0027373
 protein coding gene Chr3:90693502-90705970 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027252
 protein coding gene Chr3:102398140-102410764 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027915
 protein coding gene Chr3:88499440-88512166 (-)
PWK/PhJ MGP_PWKPhJ_G0026332
 protein coding gene Chr3:85904449-85915613 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026151
 protein coding gene Chr3:87673957-87684807 (-)
WSB/EiJ MGP_WSBEiJ_G0026680
 protein coding gene Chr3:88888510-88901055 (-)



Homology
more
  • Human Ortholog
    FLAD1, flavin adenine dinucleotide synthetase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FLAD1, flavin adenine dinucleotide synthetase 1
  • Synonyms
    FAD1, FADS, LSMFLAD, PP591
  • Links
    NCBI Gene ID: 80308
    neXtProt AC: NX_Q8NFF5
    UniProt: Q8NFF5

  • Chr Location
    1q21.3; chr1:154983338-154993111 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    9
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319945 NCBI Gene Model | MGI Sequence Detail 9209 C57BL/6J ±  kb
transcript NM_001362376 RefSeq | MGI Sequence Detail 2429 C57BL/6  
polypeptide Q8R123 UniProt | EBI | MGI Sequence Detail 492 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 2
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:335799 DELUCA C, et al., Flavin adenine dinucleotide synthesis in animal tissues. Biochim Biophys Acta. 1958 Oct;30(1):6-11
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory