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Fbxl9 Gene Detail
Summary
  • Symbol
    Fbxl9
  • Name
    F-box and leucine-rich repeat protein 9
  • Synonyms
    A630024J02Rik, FBL9, Lrrc29
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443262
    NCBI Gene: 234684
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:106038972-106052952 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 8, 53.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    368 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443262
protein coding gene Chr8:106038897-106052952 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034039
protein coding gene Chr8:107580851-107598550 (-)
A/J MGP_AJ_G0034020
protein coding gene Chr8:103290485-103301773 (-)
AKR/J MGP_AKRJ_G0033946
protein coding gene Chr8:106275629-106289157 (-)
BALB/cJ MGP_BALBcJ_G0034013
protein coding gene Chr8:103467455-103477338 (-)
C3H/HeJ MGP_C3HHeJ_G0033725
protein coding gene Chr8:107026795-107037411 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034533
protein coding gene Chr8:111531969-111545207 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031475
protein coding gene Chr8:96439531-96454104 (-)
CAST/EiJ MGP_CASTEiJ_G0033051
protein coding gene Chr8:106521723-106535190 (-)
CBA/J MGP_CBAJ_G0033698
protein coding gene Chr8:115131261-115141171 (-)
DBA/2J MGP_DBA2J_G0033853
protein coding gene Chr8:102635713-102646458 (-)
FVB/NJ MGP_FVBNJ_G0033799
protein coding gene Chr8:101560847-101573478 (-)
LP/J MGP_LPJ_G0033944
protein coding gene Chr8:107788385-107798638 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033842
protein coding gene Chr8:118342193-118351956 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034551
protein coding gene Chr8:106249846-106260075 (-)
PWK/PhJ MGP_PWKPhJ_G0032752
protein coding gene Chr8:102022313-102036445 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032593
protein coding gene Chr8:104925243-104938555 (-)
WSB/EiJ MGP_WSBEiJ_G0033167
protein coding gene Chr8:106902738-106915536 (-)



Homology
more
  • Human Ortholog
    FBXL9P, F-box and leucine rich repeat protein, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXL9P, F-box and leucine rich repeat protein, pseudogene
  • Synonyms
    FBL9, FBXL9, LRRC29
  • Links
    NCBI Gene ID: 26231

  • Chr Location
    16q22.1; chr16:67207139-67227048 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 234684 NCBI Gene Model | MGI Sequence Detail 13981 C57BL/6J ±  kb
transcript NM_001368408 RefSeq | MGI Sequence Detail 2321 C57BL/6  
polypeptide NP_001355337 RefSeq | MGI Sequence Detail 621 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • InterPro Domains
    IPR001810 F-box domain
    IPR050648 F-box/Leucine-rich repeat
    IPR036047 F-box-like domain superfamily
    IPR001611 Leucine-rich repeat
    IPR006553 Leucine-rich repeat, cysteine-containing subtype
    IPR032675 Leucine-rich repeat domain superfamily
Molecular
Reagents
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  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:7316765
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory