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Smco3 Gene Detail
Summary
  • Symbol
    Smco3
  • Name
    single-pass membrane protein with coiled-coil domains 3
  • Synonyms
    C030030A07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443451
    NCBI Gene: 654818
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:136806929-136812448 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 66.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    507 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443451
 protein coding gene Chr6:136806925-136812450 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031429
 protein coding gene Chr6:141336082-141340263 (-)
A/J no annotation
AKR/J MGP_AKRJ_G0031330
 protein coding gene Chr6:139818190-139855907 (-)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0031132
 protein coding gene Chr6:139859346-139885071 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031872
 protein coding gene Chr6:145171614-145177124 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0031092
 protein coding gene Chr6:150562256-150564170 (-)
DBA/2J MGP_DBA2J_G0031249
 protein coding gene Chr6:134574769-134590343 (-)
FVB/NJ MGP_FVBNJ_G0031200
 protein coding gene Chr6:133477535-133504811 (-)
LP/J MGP_LPJ_G0031333
 protein coding gene Chr6:141433172-141437798 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031240
 protein coding gene Chr6:154480737-154492015 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031904
 protein coding gene Chr6:139579350-139604077 (-)
PWK/PhJ MGP_PWKPhJ_G0030227
 protein coding gene Chr6:133084453-133090128 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030051
 protein coding gene Chr6:137863394-137864457 (-)
WSB/EiJ MGP_WSBEiJ_G0030593
 protein coding gene Chr6:140221625-140238177 (-)



Homology
more
  • Human Ortholog
    SMCO3, single-pass membrane protein with coiled-coil domains 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SMCO3, single-pass membrane protein with coiled-coil domains 3
  • Synonyms
    C12orf69
  • Links
    NCBI Gene ID: 440087
    neXtProt AC: NX_A2RU48
    UniProt: A2RU48

  • Chr Location
    12p12.3; chr12:14804650-14814182 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 654818 NCBI Gene Model | MGI Sequence Detail 5520 C57BL/6J ±  kb
transcript NM_001039558 RefSeq | MGI Sequence Detail 2052 C57BL/6  
polypeptide Q8BQM7 UniProt | EBI | MGI Sequence Detail 225 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000059679 single-pass membrane and coiled-coil domain-containing protein 3
    (term hierarchy)
  • InterPro Domains
    IPR027895 Protein of unknown function DUF4533
    IPR040004 Single-pass membrane and coiled-coil domain-containing protein 3
Molecular
Reagents
less
  • All nucleic 8
    Genomic 1
    cDNA 7

    Microarray probesets 3
References
more
  • Summaries
    All 21
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory