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Rpp38 Gene Detail
Summary
  • Symbol
    Rpp38
  • Name
    ribonuclease P/MRP 38 subunit
  • Synonyms
    C330006A15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443607
    NCBI Gene: 227522
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:3329986-3333680 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 1.87 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    111 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443607
protein coding gene Chr2:3328305-3334023 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025304
protein coding gene Chr2:292964-296656 (-)
A/J MGP_AJ_G0025280
protein coding gene Chr2:284999-288693 (-)
AKR/J MGP_AKRJ_G0025249
protein coding gene Chr2:284814-288508 (-)
BALB/cJ MGP_BALBcJ_G0025276
protein coding gene Chr2:265735-270155 (-)
C3H/HeJ MGP_C3HHeJ_G0025036
protein coding gene Chr2:298185-301879 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025719
protein coding gene Chr2:280966-284660 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023133
protein coding gene Chr2:234896-238568 (-)
CAST/EiJ MGP_CASTEiJ_G0024500
protein coding gene Chr2:282755-287083 (-)
CBA/J MGP_CBAJ_G0025016
protein coding gene Chr2:310651-314345 (-)
DBA/2J MGP_DBA2J_G0025147
protein coding gene Chr2:263354-267048 (-)
FVB/NJ MGP_FVBNJ_G0025109
protein coding gene Chr2:280805-284499 (-)
LP/J MGP_LPJ_G0025234
protein coding gene Chr2:302144-305836 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025142
protein coding gene Chr2:292020-296955 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025777
protein coding gene Chr2:298577-303681 (-)
PWK/PhJ MGP_PWKPhJ_G0024249
protein coding gene Chr2:266556-270250 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024051
protein coding gene Chr2:302600-306301 (-)
WSB/EiJ MGP_WSBEiJ_G0024570
protein coding gene Chr2:295250-298942 (-)



Homology
more
  • Human Ortholog
    RPP38, ribonuclease P/MRP subunit p38
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPP38, ribonuclease P/MRP subunit p38
  • Links
    NCBI Gene ID: 10557
    neXtProt AC: NX_P78345
    UniProt: P78345

  • Chr Location
    10p13; chr10:15097180-15139818 (+)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    37 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049950 Ensembl Gene Model | MGI Sequence Detail 3695 C57BL/6J ±  kb
transcript ENSMUST00000062672 Ensembl | MGI Sequence Detail 1042 Not Applicable  
polypeptide ENSMUSP00000050992 Ensembl | MGI Sequence Detail 280 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 59
    Diseases 1
    Gene Ontology 6
    Phenotypes 37
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:331385 Yao W, et al., Keratinocyte-derived cytokine TSLP promotes growth and metastasis of melanoma by regulating the tumor-associated immune microenvironment. JCI Insight. 2022 Nov 8;7(21)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory