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Zbtb11 Gene Detail
Summary
  • Symbol
    Zbtb11
  • Name
    zinc finger and BTB domain containing 11
  • Synonyms
    9230110G02Rik, ZNF-U69274
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443876
    NCBI Gene: 271377
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:55794246-55829276 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 33.74 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    891 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443876
 protein coding gene Chr16:55791820-55829276 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022884
 protein coding gene Chr16:55069540-55110864 (+)
A/J MGP_AJ_G0022851
 protein coding gene Chr16:52705452-52741415 (+)
AKR/J MGP_AKRJ_G0022823
 protein coding gene Chr16:54373025-54408018 (+)
BALB/cJ MGP_BALBcJ_G0022851
 protein coding gene Chr16:52801043-52843229 (+)
C3H/HeJ MGP_C3HHeJ_G0022614
 protein coding gene Chr16:54561025-54598418 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023299
 protein coding gene Chr16:56611383-56648151 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020810
 protein coding gene Chr16:52424855-52459043 (+)
CAST/EiJ MGP_CASTEiJ_G0022141
 protein coding gene Chr16:54963869-54999232 (+)
CBA/J MGP_CBAJ_G0022587
 protein coding gene Chr16:58881195-58920759 (+)
DBA/2J MGP_DBA2J_G0022719
 protein coding gene Chr16:52458064-52495192 (+)
FVB/NJ MGP_FVBNJ_G0022694
 protein coding gene Chr16:52222835-52261833 (+)
LP/J MGP_LPJ_G0022786
 protein coding gene Chr16:54884035-54921941 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022712
 protein coding gene Chr16:59192919-59229680 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023314
 protein coding gene Chr16:54528892-54565697 (+)
PWK/PhJ MGP_PWKPhJ_G0021880
 protein coding gene Chr16:52806845-52842702 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021710
 protein coding gene Chr16:54324874-54360693 (+)
WSB/EiJ MGP_WSBEiJ_G0022185
 protein coding gene Chr16:54553567-54589263 (+)



Homology
more
  • Human Ortholog
    ZBTB11, zinc finger and BTB domain containing 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZBTB11, zinc finger and BTB domain containing 11
  • Synonyms
    MRT69, ZNF913, ZNF-U69274
  • Links
    NCBI Gene ID: 27107
    neXtProt AC: NX_O95625
    UniProt: O95625

  • Chr Location
    3q12.3; chr3:101648889-101677135 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ZBTB11 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    744
  • Tissues
    37
  • cDNA Data
    56
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022601 Ensembl Gene Model | MGI Sequence Detail 35031 C57BL/6J ±  kb
transcript ENSMUST00000050248 Ensembl | MGI Sequence Detail 4920 Not Applicable  
polypeptide ENSMUSP00000056923 Ensembl | MGI Sequence Detail 1050 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 58
    cDNA 56
    Primer pair 1
    Other 1

    Microarray probesets 1
References
more
  • Summaries
    All 32
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:8000 Balcarek JM, et al., Structure of the mouse glial fibrillary acidic protein gene: implications for the evolution of the intermediate filament multigene family. Nucleic Acids Res. 1985 Aug 12;13(15):5527-43
  • Latest
    J:343208 Cao H, et al., Late fetal hematopoietic failure results from ZBTB11 deficiency despite abundant HSC specification. Blood Adv. 2023 Nov 14;7(21):6506-6519
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory