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Ppm1e Gene Detail
Summary
  • Symbol
    Ppm1e
  • Name
    protein phosphatase 1E (PP2C domain containing)
  • Synonyms
    B930008A12Rik, mKIAA1072, POPX1, PP2CH
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444096
    NCBI Gene: 320472
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:87117732-87249849 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 51.99 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    660 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444096
 protein coding gene Chr11:87117724-87249884 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018902
 protein coding gene Chr11:88809039-88948993 (-)
A/J MGP_AJ_G0018869
 protein coding gene Chr11:85398578-85532078 (-)
AKR/J MGP_AKRJ_G0018839
 protein coding gene Chr11:87956026-88090601 (-)
BALB/cJ MGP_BALBcJ_G0018842
 protein coding gene Chr11:85791155-85924736 (-)
C3H/HeJ MGP_C3HHeJ_G0018656
 protein coding gene Chr11:87972777-88110375 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019294
 protein coding gene Chr11:91482275-91634110 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016927
 protein coding gene Chr11:82423972-82560856 (-)
CAST/EiJ MGP_CASTEiJ_G0018211
 protein coding gene Chr11:88680478-88817643 (-)
CBA/J MGP_CBAJ_G0018627
 protein coding gene Chr11:95338312-95488159 (-)
DBA/2J MGP_DBA2J_G0018735
 protein coding gene Chr11:84956783-85089710 (-)
FVB/NJ MGP_FVBNJ_G0018724
 protein coding gene Chr11:84464142-84597385 (-)
LP/J MGP_LPJ_G0018805
 protein coding gene Chr11:89315540-89450648 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018751
 protein coding gene Chr11:95415215-95551873 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019334
 protein coding gene Chr11:88189511-88323202 (-)
PWK/PhJ MGP_PWKPhJ_G0017981
 protein coding gene Chr11:85774822-85911449 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017773
 protein coding gene Chr11:87767070-87890685 (-)
WSB/EiJ MGP_WSBEiJ_G0018262
 protein coding gene Chr11:88068052-88206400 (-)



Homology
more
  • Human Ortholog
    PPM1E, protein phosphatase, Mg2+/Mn2+ dependent 1E
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPM1E, protein phosphatase, Mg2+/Mn2+ dependent 1E
  • Synonyms
    caMKN, CaMKP-N, CAMKPN, POPX1, PP2CH
  • Links
    NCBI Gene ID: 22843
    neXtProt AC: NX_Q8WY54
    UniProt: Q8WY54

  • Chr Location
    17q22; chr17:58755854-58985179 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    758
  • Tissues
    38
  • cDNA Data
    7
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046442 Ensembl Gene Model | MGI Sequence Detail 132118 C57BL/6J ±  kb
transcript ENSMUST00000055438 Ensembl | MGI Sequence Detail 6344 Not Applicable  
polypeptide ENSMUSP00000061278 Ensembl | MGI Sequence Detail 749 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    Genomic 1
    cDNA 7
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2144485
References
more
  • Summaries
    All 43
    Developmental Gene Expression 2
    Gene Ontology 9
    Phenotypes 14
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:281175 Yorgan TA, et al., Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling. Bone. 2019 Oct;127:155-163
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory