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Dennd11 Gene Detail
Summary
  • Symbol
    Dennd11
  • Name
    DENN domain containing 11
  • Synonyms
    E330009J07Rik, mKIAA1147
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444256
    NCBI Gene: 243780
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:40378309-40413069 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 18.82 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1007 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444256
 protein coding gene Chr6:40378309-40413069 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030606
 protein coding gene Chr6:38856818-38894401 (-)
A/J MGP_AJ_G0030579
 protein coding gene Chr6:37147721-37184398 (-)
AKR/J MGP_AKRJ_G0030506
 protein coding gene Chr6:38324424-38358993 (-)
BALB/cJ MGP_BALBcJ_G0030589
 protein coding gene Chr6:37362863-37397313 (-)
C3H/HeJ MGP_C3HHeJ_G0030302
 protein coding gene Chr6:38350258-38385621 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031043
 protein coding gene Chr6:39821097-39861007 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028255
 protein coding gene Chr6:35019076-35053888 (-)
CAST/EiJ MGP_CASTEiJ_G0029704
 protein coding gene Chr6:38274619-38310374 (-)
CBA/J MGP_CBAJ_G0030280
 protein coding gene Chr6:41418578-41453342 (-)
DBA/2J MGP_DBA2J_G0030424
 protein coding gene Chr6:36959148-36993965 (-)
FVB/NJ MGP_FVBNJ_G0030378
 protein coding gene Chr6:36743944-36778339 (-)
LP/J MGP_LPJ_G0030511
 protein coding gene Chr6:38860316-38901554 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030414
 protein coding gene Chr6:43655397-43691993 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031073
 protein coding gene Chr6:38292043-38327684 (-)
PWK/PhJ MGP_PWKPhJ_G0029418
 protein coding gene Chr6:36655975-36692217 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029254
 protein coding gene Chr6:38007961-38044717 (-)
WSB/EiJ MGP_WSBEiJ_G0029780
 protein coding gene Chr6:38239646-38276808 (-)



Homology
more
  • Human Ortholog
    DENND11, DENN domain containing 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DENND11, DENN domain containing 11
  • Synonyms
    KIAA1147, LCHN, PRO2561
  • Links
    NCBI Gene ID: 57189
    neXtProt AC: NX_A4D1U4
    UniProt: A4D1U4

  • Chr Location
    7q34; chr7:141656728-141702166 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    731
  • Tissues
    4
  • cDNA Data
    54
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 243780 NCBI Gene Model | MGI Sequence Detail 34761 C57BL/6J ±  kb
transcript NM_001356375 RefSeq | MGI Sequence Detail 6742 C57BL/6  
polypeptide Q3UHG7 UniProt | EBI | MGI Sequence Detail 455 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 54
    cDNA 54

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141486, MGI:6369065
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory