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Arhgap11a Gene Detail
Summary
  • Symbol
    Arhgap11a
  • Name
    Rho GTPase activating protein 11A
  • Synonyms
    6530401L14Rik, GAP (1-12), mKIAA0013
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444300
    NCBI Gene: 228482
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:113661837-113679006 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 57.47 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    455 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444300
 protein coding gene Chr2:113661837-113679006 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026299
 protein coding gene Chr2:116311067-116326391 (-)
A/J MGP_AJ_G0026260
 protein coding gene Chr2:111576100-111591575 (-)
AKR/J MGP_AKRJ_G0026239
 protein coding gene Chr2:114683079-114699753 (-)
BALB/cJ MGP_BALBcJ_G0026273
 protein coding gene Chr2:111807357-111822714 (-)
C3H/HeJ MGP_C3HHeJ_G0026018
 protein coding gene Chr2:115105630-115121105 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026720
 protein coding gene Chr2:120165708-120181032 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024100
 protein coding gene Chr2:106740559-106757698 (-)
CAST/EiJ MGP_CASTEiJ_G0025481
 protein coding gene Chr2:115405081-115422881 (-)
CBA/J MGP_CBAJ_G0025995
 protein coding gene Chr2:124358824-124374299 (-)
DBA/2J MGP_DBA2J_G0026134
 protein coding gene Chr2:111033008-111048365 (-)
FVB/NJ MGP_FVBNJ_G0026096
 protein coding gene Chr2:109884003-109900677 (-)
LP/J MGP_LPJ_G0026235
 protein coding gene Chr2:116610669-116625993 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026115
 protein coding gene Chr2:128746457-128764022 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026775
 protein coding gene Chr2:114755642-114770999 (-)
PWK/PhJ MGP_PWKPhJ_G0025217
 protein coding gene Chr2:110540959-110557834 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025016
 protein coding gene Chr2:113906729-113923281 (-)
WSB/EiJ MGP_WSBEiJ_G0025550
 protein coding gene Chr2:115574658-115592592 (-)



Homology
more
  • Human Ortholog
    ARHGAP11A, Rho GTPase activating protein 11A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARHGAP11A, Rho GTPase activating protein 11A
  • Synonyms
    GAP (1-12)
  • Links
    NCBI Gene ID: 9824
    neXtProt AC: NX_Q6P4F7
    UniProt: Q6P4F7

  • Chr Location
    15q13.3; chr15:32615144-32639941 (+)  GRCh38
  • Human Ortholog
    ARHGAP11B, Rho GTPase activating protein 11B
  • Synonyms
    B'-T, FAM7B1, GAP (1-8)
  • Links
    NCBI Gene ID: 89839
    neXtProt AC: NX_Q3KRB8
    UniProt: Q3KRB8

  • Chr Location
    15q13.2; chr15:30624494-30649529 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from multigenic genotypes
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1123
  • Tissues
    197
  • cDNA Data
    12
  • Literature Summary
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 228482 NCBI Gene Model | MGI Sequence Detail 17170 C57BL/6J ±  kb
transcript NM_181416 RefSeq | MGI Sequence Detail 5017 C57BL/6  
polypeptide Q80Y19 UniProt | EBI | MGI Sequence Detail 987 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 13
    Primer pair 2
    Other 2

    Microarray probesets 3
References
more
  • Summaries
    All 39
    Developmental Gene Expression 9
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:347584 Xing L, et al., Functional synergy of a human-specific and an ape-specific metabolic regulator in human neocortex development. Nat Commun. 2024 Apr 24;15(1):3468
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory