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Cfap46 Gene Detail
Summary
  • Symbol
    Cfap46
  • Name
    cilia and flagella associated protein 46
  • Synonyms
    9330101J02Rik, E030019B06Rik, Ttc40
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444387
    NCBI Gene: 212124
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:139180867-139263733 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 84.57 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2563 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444387
 protein coding gene Chr7:139180830-139264701 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033152
 protein coding gene Chr7:144633162-144732740 (-)
A/J MGP_AJ_G0033134
 protein coding gene Chr7:140547745-140634444 (-)
AKR/J MGP_AKRJ_G0033066
 protein coding gene Chr7:144355968-144446047 (-)
BALB/cJ MGP_BALBcJ_G0033135
 protein coding gene Chr7:140292677-140377742 (-)
C3H/HeJ MGP_C3HHeJ_G0032849
 protein coding gene Chr7:144164936-144258853 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033646
 protein coding gene Chr7:149972127-150065432 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030619
 protein coding gene Chr7:141680339-141764644 (-)
CAST/EiJ MGP_CASTEiJ_G0032179
 protein coding gene Chr7:136455629-136554385 (-)
CBA/J MGP_CBAJ_G0032822
 protein coding gene Chr7:155029681-155132777 (-)
DBA/2J MGP_DBA2J_G0032974
 protein coding gene Chr7:138503623-138592066 (-)
FVB/NJ MGP_FVBNJ_G0032927
 protein coding gene Chr7:138389921-138473667 (-)
LP/J MGP_LPJ_G0033068
 protein coding gene Chr7:146183393-146280711 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032959
 protein coding gene Chr7:155722026-155815063 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033666
 protein coding gene Chr7:143342947-143442797 (-)
PWK/PhJ MGP_PWKPhJ_G0031885
 protein coding gene Chr7:131675182-131760564 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031730
 protein coding gene Chr7:130182350-130269933 (-)
WSB/EiJ MGP_WSBEiJ_G0032290
 protein coding gene Chr7:144262413-144352129 (-)



Homology
more
  • Human Ortholog
    CFAP46, cilia and flagella associated protein 46
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CFAP46, cilia and flagella associated protein 46
  • Synonyms
    bA288G11.4, bA288G11.5, bB137A17.2, bB137A17.3, C10orf123, C10orf124, C10orf92, C10orf93, TTC40
  • Links
    NCBI Gene ID: 54777
    neXtProt AC: NX_Q8IYW2
    UniProt: Q8IYW2

  • Chr Location
    10q26.3; chr10:132808392-132942823 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049571 Ensembl Gene Model | MGI Sequence Detail 82867 C57BL/6J ±  kb
transcript ENSMUST00000129990 Ensembl | MGI Sequence Detail 8180 Not Applicable  
polypeptide ENSMUSP00000120186 Ensembl | MGI Sequence Detail 2641 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    12 Sequences
  • InterPro Domains
    IPR039586 Cilia- and flagella-associated protein 46
  • GlyGen
    E9Q2C0 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 2
Other
Accession IDs
less
MGI:2685016
References
more
  • Summaries
    All 28
    Phenotypes 12
  • Earliest
    J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory