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Dcaf12l1 Gene Detail
Summary
  • Symbol
    Dcaf12l1
  • Name
    DDB1 and CUL4 associated factor 12-like 1
  • Synonyms
    A230038L21Rik, Wdr40b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444462
    NCBI Gene: 245404
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:43875447-43879074 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 24.00 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    132 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444462
 protein coding gene ChrX:43875444-43879074 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035681
 protein coding gene ChrX:39857795-39861422 (-)
A/J MGP_AJ_G0035664
 protein coding gene ChrX:39775152-39778779 (-)
AKR/J MGP_AKRJ_G0035584
 protein coding gene ChrX:40792796-40797985 (-)
BALB/cJ MGP_BALBcJ_G0035650
 protein coding gene ChrX:39479878-39483505 (-)
C3H/HeJ MGP_C3HHeJ_G0035354
 protein coding gene ChrX:40170368-40173995 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036179
 protein coding gene ChrX:40795357-40798984 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033031
 protein coding gene ChrX:37682287-37685922 (-)
CAST/EiJ MGP_CASTEiJ_G0034645
 protein coding gene ChrX:27917535-27921164 (-)
CBA/J MGP_CBAJ_G0035328
 protein coding gene ChrX:41932750-41936377 (-)
DBA/2J MGP_DBA2J_G0035482
 protein coding gene ChrX:39582936-39586563 (-)
FVB/NJ MGP_FVBNJ_G0035431
 protein coding gene ChrX:39380604-39384231 (-)
LP/J MGP_LPJ_G0035570
 protein coding gene ChrX:40173196-40176823 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035469
 protein coding gene ChrX:42997665-43001292 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036197
 protein coding gene ChrX:39801046-39804673 (-)
PWK/PhJ MGP_PWKPhJ_G0034344
 protein coding gene ChrX:27389713-27393468 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034189
 protein coding gene ChrX:28512636-28516266 (-)
WSB/EiJ MGP_WSBEiJ_G0034789
 protein coding gene ChrX:39428702-39432329 (-)



Homology
more
  • Human Ortholog
    DCAF12L1, DDB1 and CUL4 associated factor 12 like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DCAF12L1, DDB1 and CUL4 associated factor 12 like 1
  • Synonyms
    KIAA1892L, WDR40B
  • Links
    NCBI Gene ID: 139170
    neXtProt AC: NX_Q5VU92
    UniProt: Q5VU92

  • Chr Location
    Xq25; chrX:126549383-126552814 (-)  GRCh38
  • Human Ortholog
    DCAF12L2, DDB1 and CUL4 associated factor 12 like 2
  • Synonyms
    WDR40C
  • Links
    NCBI Gene ID: 340578
    neXtProt AC: NX_Q5VW00
    UniProt: Q5VW00

  • Chr Location
    Xq25; chrX:126163499-126166289 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Male mice exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    17
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045284 Ensembl Gene Model | MGI Sequence Detail 3628 C57BL/6J ±  kb
transcript ENSMUST00000060481 Ensembl | MGI Sequence Detail 3509 Not Applicable  
polypeptide ENSMUSP00000062991 Ensembl | MGI Sequence Detail 501 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR051191 DDB1-CUL4-associated factor 12
    IPR001680 WD40 repeat
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 19
    cDNA 17
    Primer pair 1
    Other 1

    Microarray probesets 5
References
more
  • Summaries
    All 25
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:327149 Houston BJ, et al., DDB1- and CUL4-associated factor 12-like protein 1 (Dcaf12l1) is not essential for male fertility in mice. Dev Biol. 2022 Jul 15;490:66-72
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory