Spata33 MGI Mouse Gene Detail - MGI:2444920 - spermatogenesis associated 33

Symbol

Spata33
Name

spermatogenesis associated 33
Synonyms

4732415M23Rik

Feature Type

protein coding gene
IDs

MGI:2444920
NCBI Gene: 320869
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr8:123939572-123948784 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 8, 72.08 cM
Mapping Data

2 experiments

SNPs within 2kb

294 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2444920	protein coding gene	Chr8:123939571-123948785 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0034246	protein coding gene	Chr8:126807677-126819344 (+)
A/J	MGP_AJ_G0034226	protein coding gene	Chr8:121558490-121568462 (+)
AKR/J	MGP_AKRJ_G0034153	protein coding gene	Chr8:125091107-125100027 (+)
BALB/cJ	MGP_BALBcJ_G0034220	protein coding gene	Chr8:121768075-121777677 (+)
C3H/HeJ	MGP_C3HHeJ_G0033930	protein coding gene	Chr8:125792252-125801840 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0034739	protein coding gene	Chr8:131054216-131065090 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031681	protein coding gene	Chr8:114373292-114389552 (+)
CAST/EiJ	MGP_CASTEiJ_G0033258	protein coding gene	Chr8:125871241-125882922 (+)
CBA/J	MGP_CBAJ_G0033903	protein coding gene	Chr8:135859501-135871903 (+)
DBA/2J	MGP_DBA2J_G0034060	protein coding gene	Chr8:120737097-120746197 (+)
FVB/NJ	MGP_FVBNJ_G0034003	protein coding gene	Chr8:119901103-119910393 (+)
LP/J	MGP_LPJ_G0034149	protein coding gene	Chr8:126941045-126951933 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0034050	protein coding gene	Chr8:138003762-138017898 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0034758	protein coding gene	Chr8:125301801-125312329 (+)
PWK/PhJ	MGP_PWKPhJ_G0032959	protein coding gene	Chr8:120570078-120579724 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0032799	protein coding gene	Chr8:124014258-124029497 (+)
WSB/EiJ	MGP_WSBEiJ_G0033374	protein coding gene	Chr8:126036494-126047051 (+)

Human Ortholog

SPATA33, spermatogenesis associated 33

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SPATA33, spermatogenesis associated 33
Synonyms

C16orf55
Links

HGNC:26463

NCBI Gene ID: 124045

neXtProt AC: NX_Q96N06

UniProt: Q96N06
Chr Location

16q24.3; chr16:89657740-89671272 (+) GRCh38

MGI Vertebrate Homology

Spata33 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: SPATA33
Gene Tree

Spata33

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Phenotype Summary

5 phenotypes from 2 alleles in 2 genetic backgrounds
4 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

6
Endonuclease-mediated

4
Targeted

1
Transgenic

1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

17 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Mice homozygous for a null allele exhibit reduced male fertility with inflexible midpieces and reduced sperm motility.

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All GO Annotations

19
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

60

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

61
RefSeq

10
UniProt

8
CCDS

CCDS40510.1

Ensembl

ENSMUSG00000048478 (Evidence)
NCBI Gene

320869

			Length	Strain/Species	Flank
genomic	320869	NCBI Gene Model \| MGI Sequence Detail	9213	C57BL/6J	± kb
transcript	NM_177279	RefSeq \| MGI Sequence Detail	518	C57BL/6
polypeptide	Q8C624	UniProt \| EBI \| MGI Sequence Detail	132	Not Applicable

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UniProt

8 Sequences
Protein Ontology

PR:000050571 spermatogenesis-associated protein 33

(term hierarchy)
InterPro Domains

IPR027930 Protein of unknown function DUF4609

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All nucleic 60

cDNA 60

Microarray probesets 4

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MGI:2142628

Summaries

All 26

Gene Ontology 5

Phenotypes 4
Earliest

J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
Latest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Spata33:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr79927	Chr8:123939565-123939587 (+)	4 bp
Tssr79928	Chr8:123939590-123939595 (+)	21 bp
Tssr79929	Chr8:123939596-123939650 (+)	51 bp
Tssr79930	Chr8:123939652-123939663 (+)	86 bp
Tssr79931	Chr8:123939753-123939771 (+)	190 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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