Zfp605 MGI Mouse Gene Detail - MGI:2444933

Symbol

Zfp605
Name

zinc finger protein 605
Synonyms

A830023I12Rik

Feature Type

protein coding gene
IDs

MGI:2444933
NCBI Gene: 675812
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr5:110257958-110277660 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 53.30 cM
Mapping Data

1 experiment

SNPs within 2kb

652 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2444933	protein coding gene	Chr5:110257898-110279402 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0029878	protein coding gene	Chr5:112531165-112565989 (+)
A/J	MGP_AJ_G0029844	protein coding gene	Chr5:108187528-108207999 (+)
AKR/J	MGP_AKRJ_G0029782	protein coding gene	Chr5:111631650-111651084 (+)
BALB/cJ	MGP_BALBcJ_G0029855	protein coding gene	Chr5:109557832-109578258 (+)
C3H/HeJ	MGP_C3HHeJ_G0029575	protein coding gene	Chr5:112056214-112079696 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0030308	protein coding gene	Chr5:116990683-117011047 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027537	protein coding gene	Chr5:103016311-103033277 (+)
CAST/EiJ	MGP_CASTEiJ_G0028983	protein coding gene	Chr5:110923269-110942848 (+)
CBA/J	MGP_CBAJ_G0029542	protein coding gene	Chr5:121388326-121408812 (+)
DBA/2J	MGP_DBA2J_G0029692	protein coding gene	Chr5:108250809-108276537 (+)
FVB/NJ	MGP_FVBNJ_G0029649	protein coding gene	Chr5:106930911-106953897 (+)
LP/J	MGP_LPJ_G0029780	protein coding gene	Chr5:113103387-113130668 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0029680	protein coding gene	Chr5:126046328-126070695 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0030349	protein coding gene	Chr5:111061491-111086741 (+)
PWK/PhJ	MGP_PWKPhJ_G0028697	protein coding gene	Chr5:106858272-106864073 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0028535	protein coding gene	Chr5:108531593-108548674 (+)
WSB/EiJ	MGP_WSBEiJ_G0029059	protein coding gene	Chr5:111514606-111535674 (+)

Human Ortholog

ZNF605, zinc finger protein 605

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZNF605, zinc finger protein 605
Links

HGNC:28068

NCBI Gene ID: 100289635

neXtProt AC: NX_Q86T29

UniProt: Q86T29
Chr Location

chr12:132918306-132956306 (-) GRCh38

MGI Vertebrate Homology

Zfp605 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: ZNF605
Gene Tree

Zfp605

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
13 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

13
Chemically induced (other)

1
Endonuclease-mediated

3
Gene trapped

6
Radiation induced

1
Spontaneous

1
Targeted

1
Genomic Mutations

2 involving Zfp605
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

40 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

2
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

14

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

GEO

Expression Atlas

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All Sequences

48
RefSeq

12
UniProt

5
CCDS

CCDS51605.1

Ensembl

ENSMUSG00000023284 (Evidence)
NCBI Gene

675812

			Length	Strain/Species	Flank
genomic	ENSMUSG00000023284	Ensembl Gene Model \| MGI Sequence Detail	19703	C57BL/6J	± kb
transcript	ENSMUST00000112528	Ensembl \| MGI Sequence Detail	3158	Not Applicable
polypeptide	ENSMUSP00000108147	Ensembl \| MGI Sequence Detail	694	Not Applicable

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UniProt

5 Sequences
InterPro Domains

IPR036051 KRAB domain superfamily

IPR001909 Krueppel-associated box

IPR050169 Krueppel C2H2-type zinc-finger

IPR036236 Zinc finger C2H2 superfamily

IPR013087 Zinc finger C2H2-type

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All nucleic 14

cDNA 14

Microarray probesets 2

Summaries

All 27

Gene Ontology 1

Phenotypes 13
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:267654 Saul MC, et al., Genomic variants in an inbred mouse model predict mania-like behaviors. PLoS One. 2018;13(5):e0197624

TSS for Zfp605:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr47867	Chr5:110257934-110257980 (+)	-1 bp
Tssr47868	Chr5:110257982-110258006 (+)	36 bp
Tssr47869	Chr5:110258133-110258164 (+)	191 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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