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Dennd2a Gene Detail
Summary
  • Symbol
    Dennd2a
  • Name
    DENN domain containing 2A
  • Synonyms
    B930096L08Rik, mKIAA1277
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444961
    NCBI Gene: 209773
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:39439312-39534801 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 18.26 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2758 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444961
 protein coding gene Chr6:39439308-39535067 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030598
 protein coding gene Chr6:37849033-37957084 (-)
A/J MGP_AJ_G0030571
 protein coding gene Chr6:36194154-36288916 (-)
AKR/J MGP_AKRJ_G0030498
 protein coding gene Chr6:37351259-37451931 (-)
BALB/cJ MGP_BALBcJ_G0030581
 protein coding gene Chr6:36415152-36512005 (-)
C3H/HeJ MGP_C3HHeJ_G0030294
 protein coding gene Chr6:37369136-37475076 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031035
 protein coding gene Chr6:38788042-38897256 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028247
 protein coding gene Chr6:34091686-34186931 (-)
CAST/EiJ MGP_CASTEiJ_G0029696
 protein coding gene Chr6:37271307-37374022 (-)
CBA/J MGP_CBAJ_G0030272
 protein coding gene Chr6:40322565-40446698 (-)
DBA/2J MGP_DBA2J_G0030416
 protein coding gene Chr6:36013187-36109203 (-)
FVB/NJ MGP_FVBNJ_G0030370
 protein coding gene Chr6:35802012-35898676 (-)
LP/J MGP_LPJ_G0030503
 protein coding gene Chr6:37877582-37979085 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030406
 protein coding gene Chr6:42640065-42742897 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031065
 protein coding gene Chr6:37301388-37400847 (-)
PWK/PhJ MGP_PWKPhJ_G0029410
 protein coding gene Chr6:35699385-35796799 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029246
 protein coding gene Chr6:37024190-37125643 (-)
WSB/EiJ MGP_WSBEiJ_G0029772
 protein coding gene Chr6:37247846-37353571 (-)



Homology
more
  • Human Ortholog
    DENND2A, DENN domain containing 2A
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DENND2A, DENN domain containing 2A
  • Synonyms
    FAM31D, KIAA1277
  • Links
    NCBI Gene ID: 27147
    neXtProt AC: NX_Q9ULE3
    UniProt: Q9ULE3

  • Chr Location
    7q34; chr7:140518419-140673993 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    94
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038456 Ensembl Gene Model | MGI Sequence Detail 95490 C57BL/6J ±  kb
transcript ENSMUST00000036877 Ensembl | MGI Sequence Detail 4468 Not Applicable  
polypeptide ENSMUSP00000045367 Ensembl | MGI Sequence Detail 1000 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 94
    cDNA 94

    Microarray probesets 4
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory