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Zc3h7a Gene Detail
Summary
  • Symbol
    Zc3h7a
  • Name
    zinc finger CCCH type containing 7 A
  • Synonyms
    A430104C18Rik, Zc3h7
  • Feature Type
    protein coding gene
  • IDs
    MGI:2445044
    NCBI Gene: 106205
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:10954458-10994257 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 6.35 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    886 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2445044
 protein coding gene Chr16:10954456-10994257 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022521
 protein coding gene Chr16:7987948-8032247 (-)
A/J MGP_AJ_G0022483
 protein coding gene Chr16:7549992-7590346 (-)
AKR/J MGP_AKRJ_G0022459
 protein coding gene Chr16:7900086-7941117 (-)
BALB/cJ MGP_BALBcJ_G0022487
 protein coding gene Chr16:7690064-7730238 (-)
C3H/HeJ MGP_C3HHeJ_G0022254
 protein coding gene Chr16:7976396-8017093 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022936
 protein coding gene Chr16:8154196-8196341 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020456
 protein coding gene Chr16:7708919-7748579 (-)
CAST/EiJ MGP_CASTEiJ_G0021781
 protein coding gene Chr16:7999940-8043621 (-)
CBA/J MGP_CBAJ_G0022223
 protein coding gene Chr16:8504815-8543796 (-)
DBA/2J MGP_DBA2J_G0022354
 protein coding gene Chr16:7557402-7596410 (-)
FVB/NJ MGP_FVBNJ_G0022330
 protein coding gene Chr16:7548838-7588675 (-)
LP/J MGP_LPJ_G0022422
 protein coding gene Chr16:7944507-7984898 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022352
 protein coding gene Chr16:8196431-8242197 (-)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0021521
 protein coding gene Chr16:7775522-7819159 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021351
 protein coding gene Chr16:7907959-7943098 (-)
WSB/EiJ MGP_WSBEiJ_G0021829
 protein coding gene Chr16:7934710-7974897 (-)



Homology
more
  • Human Ortholog
    ZC3H7A, zinc finger CCCH-type containing 7A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZC3H7A, zinc finger CCCH-type containing 7A
  • Synonyms
    HSPC055, ZC3H7, ZC3HDC7
  • Links
    NCBI Gene ID: 29066
    neXtProt AC: NX_Q8IWR0
    UniProt: Q8IWR0

  • Chr Location
    16p13.13; chr16:11750586-11797258 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    823
  • Tissues
    21
  • cDNA Data
    171
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 106205 NCBI Gene Model | MGI Sequence Detail 39800 C57BL/6J ±  kb
transcript NR_027502 RefSeq | MGI Sequence Detail 3795 C57BL/6  
polypeptide NP_666043 RefSeq | MGI Sequence Detail 970 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    14 Sequences
  • InterPro Domains
    IPR011990 Tetratricopeptide-like helical domain superfamily
    IPR019734 Tetratricopeptide repeat
    IPR036236 Zinc finger C2H2 superfamily
    IPR013087 Zinc finger C2H2-type
    IPR039691 Zinc finger CCCH domain-containing protein A/B
    IPR000571 Zinc finger, CCCH-type
    IPR036855 Zinc finger, CCCH-type superfamily
Molecular
Reagents
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  • All nucleic 171
    cDNA 171

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146432, MGI:2146666
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory