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H2ac4 Gene Detail
Summary
  • Symbol
    H2ac4
  • Name
    H2A clustered histone 4
  • Synonyms
    H2A.1, H2a-53, Hist1h2ab
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448306
    NCBI Gene: 319172
  • Member of
    Hist1 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23935109-23935581 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 9.91 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    159 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448306
 protein coding gene Chr13:23935061-23935581 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020362
 protein coding gene Chr13:21194015-21195571 (+)
A/J no annotation
AKR/J MGP_AKRJ_G0020292
 protein coding gene Chr13:21057935-21058284 (+)
BALB/cJ MGP_BALBcJ_G0020309
 protein coding gene Chr13:20793114-20793586 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0020747
 protein coding gene Chr13:21974258-21974730 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018334
 protein coding gene Chr13:19578680-19579129 (+)
CAST/EiJ MGP_CASTEiJ_G0019632
 protein coding gene Chr13:20810536-20811485 (+)
CBA/J MGP_CBAJ_G0020068
 protein coding gene Chr13:22827272-22827705 (+)
DBA/2J MGP_DBA2J_G0020193
 protein coding gene Chr13:20332417-20332903 (+)
FVB/NJ MGP_FVBNJ_G0020177
 protein coding gene Chr13:19982614-19983415 (+)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0020788
 protein coding gene Chr13:20909730-20910202 (+)
PWK/PhJ MGP_PWKPhJ_G0019386
 protein coding gene Chr13:20360464-20361037 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0019690
 protein coding gene Chr13:21047844-21048303 (+)



Homology
more
  • Human Ortholog
    H2AC4, H2A clustered histone 4
  • Vertebrate Orthologs
    14
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H2AC4, H2A clustered histone 4
  • Synonyms
    H2AC8, H2AFM, H2A/m, HIST1H2AB
  • Links
    NCBI Gene ID: 8335
    neXtProt AC: NX_P04908
    UniProt: P04908

  • Chr Location
    6p22.2; chr6:26033092-26033618 (-)  GRCh38
  • Human Ortholog
    H2AC7, H2A clustered histone 7
  • Synonyms
    H2A.3, H2AFG, H2A/g, HIST1H2AD
  • Links
    NCBI Gene ID: 3013
    neXtProt AC: NX_P20671
    UniProt: P20671

  • Chr Location
    6p22.2; chr6:26198784-26199293 (-)  GRCh38
  • Human Ortholog
    H2AC8, H2A clustered histone 8
  • Synonyms
    H2A.1, H2A.2, H2A/a, H2AC4, H2AFA, HIST1H2AE
  • Links
    NCBI Gene ID: 3012
    neXtProt AC: NX_P04908
    UniProt: P04908

  • Chr Location
    6p22.2; chr6:26216921-26217437 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving H2ac4
  • Find Mice (IMSR)
    3 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    2
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000061615 Ensembl Gene Model | MGI Sequence Detail 473 C57BL/6J ±  kb
transcript ENSMUST00000078369 Ensembl | MGI Sequence Detail 473 Not Applicable  
polypeptide ENSMUSP00000077477 Ensembl | MGI Sequence Detail 130 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 4
    Genomic 1
    cDNA 2
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:6324966
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:320332 Kujirai T, et al., Transcription through the nucleosome. Curr Opin Struct Biol. 2020 Apr;61:42-49
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory