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H3c6 Gene Detail
Summary
  • Symbol
    H3c6
  • Name
    H3 clustered histone 6
  • Synonyms
    H3.1, H3-f, Hist1h3e
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448326
    NCBI Gene: 319151
  • Member of
    Hist1 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23745708-23746543 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 9.79 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    141 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448326
 protein coding gene Chr13:23745649-23746559 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0020289
 protein coding gene Chr13:20562755-20573074 (+)
C3H/HeJ MGP_C3HHeJ_G0020100
 protein coding gene Chr13:20908423-20909268 (+)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0018320
 protein coding gene Chr13:19402984-19403773 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0020049
 protein coding gene Chr13:22554206-22570838 (+)
DBA/2J MGP_DBA2J_G0020176
 protein coding gene Chr13:20124935-20127118 (+)
FVB/NJ MGP_FVBNJ_G0020162
 protein coding gene Chr13:19761311-19771390 (+)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0020764
 protein coding gene Chr13:20673024-20685691 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0019188
 protein coding gene Chr13:19497758-19498556 (-)
WSB/EiJ MGP_WSBEiJ_G0019678
 protein coding gene Chr13:20839867-20841418 (-)



Homology
more
  • Human Ortholog
    H3C11, H3 clustered histone 11
  • Vertebrate Orthologs
    14
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H3C11, H3 clustered histone 11
  • Synonyms
    H3C1, H3C10, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3.f, H3/f, H3FF, HIST1H3I
  • Links
    NCBI Gene ID: 8354
    neXtProt AC: NX_P68431
    UniProt: P68431

  • Chr Location
    6p22.1; chr6:27871845-27872346 (-)  GRCh38
  • Human Ortholog
    H3C13, H3 clustered histone 13
  • Synonyms
    H3C14, H3C15, HIST2H3D
  • Links
    NCBI Gene ID: 653604
    neXtProt AC: NX_Q71DI3
    UniProt: Q71DI3

  • Chr Location
    1q21.2; chr1:149813225-149813693 (-)  GRCh38
  • Human Ortholog
    H3C14, H3 clustered histone 14
  • Synonyms
    H3, H3.2, H3C13, H3C15, H3F2, H3FM, H3FN, H3/M, HIST2H3C
  • Links
    NCBI Gene ID: 126961
    neXtProt AC: NX_Q71DI3
    UniProt: Q71DI3

  • Chr Location
    1q21.2
  • Human Ortholog
    H3C15, H3 clustered histone 15
  • Synonyms
    H3C13, H3C14, H3/n, H3/o, HIST2H3A
  • Links
    NCBI Gene ID: 333932
    neXtProt AC: NX_Q71DI3
    UniProt: Q71DI3

  • Chr Location
    1q21.2; chr1:149852608-149853125 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving H3c6
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    8 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    722
  • Tissues
    15
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000069273 Ensembl Gene Model | MGI Sequence Detail 836 C57BL/6J ±  kb
transcript ENSMUST00000105107 Ensembl | MGI Sequence Detail 836 Not Applicable  
polypeptide ENSMUSP00000100739 Ensembl | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 5
    Genomic 1
    cDNA 3
    Primer pair 1
Other
Accession IDs
less
MGI:6324983
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:321942 Denoth-Lippuner A, et al., Visualization of individual cell division history in complex tissues using iCOUNT. Cell Stem Cell. 2021 Nov 4;28(11):2020-2034.e12
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory