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H2bc3 Gene Detail
Summary
  • Symbol
    H2bc3
  • Name
    H2B clustered histone 3
  • Synonyms
    H2b-143, Hist1h2bb
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448377
    NCBI Gene: 319178
  • Member of
    Hist1 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23930717-23931206 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 9.90 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    193 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448377
 protein coding gene Chr13:23930717-23931224 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020361
 protein coding gene Chr13:21189688-21190139 (+)
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0020036
 protein coding gene Chr13:18979334-18979628 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020746
 protein coding gene Chr13:21969455-21970373 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018333
 protein coding gene Chr13:19574410-19574860 (+)
CAST/EiJ MGP_CASTEiJ_G0019631
 protein coding gene Chr13:20806209-20806660 (+)
CBA/J MGP_CBAJ_G0020000
 protein coding gene Chr13:20336756-20337050 (-)
DBA/2J MGP_DBA2J_G0020120
 protein coding gene Chr13:18203745-18204239 (-)
FVB/NJ MGP_FVBNJ_G0020102
 protein coding gene Chr13:17867594-17868088 (-)
LP/J MGP_LPJ_G0020266
 protein coding gene Chr13:21498642-21499100 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0020787
 protein coding gene Chr13:20905403-20905854 (+)
PWK/PhJ MGP_PWKPhJ_G0019385
 protein coding gene Chr13:20356026-20356478 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019201
 protein coding gene Chr13:19707119-19712956 (+)
WSB/EiJ MGP_WSBEiJ_G0019689
 protein coding gene Chr13:21043515-21043967 (+)



Homology
more
  • Human Ortholog
    H2BC14, H2B clustered histone 14
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H2BC14, H2B clustered histone 14
  • Synonyms
    dJ160A22.3, H2B/e, H2BFE, HIST1H2BM
  • Links
    NCBI Gene ID: 8342
    neXtProt AC: NX_Q99879
    UniProt: Q99879

  • Chr Location
    6p22.1; chr6:27815022-27815489 (+)  GRCh38
  • Human Ortholog
    H2BC15, H2B clustered histone 15
  • Synonyms
    H2B/d, H2BFD, HIST1H2BN
  • Links
    NCBI Gene ID: 8341
    neXtProt AC: NX_Q99877
    UniProt: Q99877

  • Chr Location
    6p22.1; chr6:27838545-27855709 (+)  GRCh38
  • Human Ortholog
    H2BC3, H2B clustered histone 3
  • Synonyms
    H2B.1, H2B/f, H2BFF, HIST1H2BB
  • Links
    NCBI Gene ID: 3018
    neXtProt AC: NX_P33778
    UniProt: P33778

  • Chr Location
    6p22.2; chr6:26043227-26043713 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319178 NCBI Gene Model | MGI Sequence Detail 490 C57BL/6J ±  kb
transcript NM_175664 RefSeq | MGI Sequence Detail 490 C57BL/6  
polypeptide Q64475 UniProt | EBI | MGI Sequence Detail 126 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    Genomic 1
    cDNA 2

    Microarray probesets 1
Other
Accession IDs
less
MGI:6324967
References
more
  • Summaries
    All 28
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:141688 Goldsworthy M, et al., Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance. Diabetes. 2008 Aug;57(8):2234-44
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory