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H4c3 Gene Detail
Summary
  • Symbol
    H4c3
  • Name
    H4 clustered histone 3
  • Synonyms
    Hist1h4c
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448421
    NCBI Gene: 319155
  • Member of
    Hist1 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23882067-23882441 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 9.88 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    121 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448421
 protein coding gene Chr13:23881618-23882441 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020358
 protein coding gene Chr13:21133500-21133897 (-)
A/J MGP_AJ_G0020309
 protein coding gene Chr13:20745284-20745806 (-)
AKR/J MGP_AKRJ_G0020289
 protein coding gene Chr13:21000364-21000761 (-)
BALB/cJ MGP_BALBcJ_G0020305
 protein coding gene Chr13:20737530-20737927 (-)
C3H/HeJ MGP_C3HHeJ_G0020110
 protein coding gene Chr13:21067460-21068812 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020743
 protein coding gene Chr13:21911231-21911625 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018329
 protein coding gene Chr13:19531028-19531421 (-)
CAST/EiJ MGP_CASTEiJ_G0019627
 protein coding gene Chr13:20752137-20753410 (-)
CBA/J MGP_CBAJ_G0020061
 protein coding gene Chr13:22764125-22764522 (-)
DBA/2J MGP_DBA2J_G0020189
 protein coding gene Chr13:20277114-20277511 (-)
FVB/NJ MGP_FVBNJ_G0020173
 protein coding gene Chr13:19929753-19930150 (-)
LP/J MGP_LPJ_G0020263
 protein coding gene Chr13:21443993-21446959 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020201
 protein coding gene Chr13:23060633-23062828 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020783
 protein coding gene Chr13:20849607-20852350 (-)
PWK/PhJ MGP_PWKPhJ_G0019381
 protein coding gene Chr13:20304234-20305020 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019197
 protein coding gene Chr13:19646009-19647695 (-)
WSB/EiJ MGP_WSBEiJ_G0019685
 protein coding gene Chr13:20992442-20992836 (-)



Homology
more
  • Human Ortholog
    H4C5, H4 clustered histone 5
  • Vertebrate Orthologs
    16
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H4C5, H4 clustered histone 5
  • Synonyms
    H4-16, H4C1, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, H4C2, H4C3, H4C4, H4C6, H4C8, H4C9, H4FJ, H4/j, HIST1H4E, TEBIVANED3, TEVANED3
  • Links
    NCBI Gene ID: 8367
    neXtProt AC: NX_P62805
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26204610-26205021 (+)  GRCh38
  • Human Ortholog
    H4C6, H4 clustered histone 6
  • Synonyms
    H4, H4-16, H4/c, H4C1, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, H4C2, H4C3, H4C4, H4C5, H4C8, H4C9, H4FC, HIST1H4F
  • Links
    NCBI Gene ID: 8361
    neXtProt AC: NX_P62805
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26240393-26240793 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    777
  • Tissues
    35
  • cDNA Data
    8
  • Literature Summary
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319155 NCBI Gene Model | MGI Sequence Detail 375 C57BL/6J ±  kb
transcript NM_178208 RefSeq | MGI Sequence Detail 375 C57BL/6  
polypeptide P62806 UniProt | EBI | MGI Sequence Detail 103 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 13
    Genomic 2
    cDNA 8
    Primer pair 1
    Other 2

    Microarray probesets 1
Other
Accession IDs
less
MGI:6324970
References
more
  • Summaries
    All 36
    Developmental Gene Expression 12
    Gene Ontology 1
    Phenotypes 9
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:228639 Blackburn J, et al., Excess NF-kappaB induces ectopic odontogenesis in embryonic incisor epithelium. J Dent Res. 2015 Jan;94(1):121-8
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory