H4c6 Gene Detail

Summary

• Symbol
  H4c6
• Name
  H4 clustered histone 6
• Synonyms
  Hist1h4f

• Feature Type
  protein coding gene
• IDs
  MGI:2448425
  NCBI Gene: 319157
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr13:23735460-23735842 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 13, 9.78 cM, cytoband A2-A3
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  113 from dbSNP Build 142
• Strain Annotations
  17

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2448425	protein coding gene	Chr13:23735432-23735842 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0020348	protein coding gene	Chr13:20968199-20968589 (-)
A/J	MGP_AJ_G0020303	protein coding gene	Chr13:20590318-20591133 (-)
AKR/J	MGP_AKRJ_G0020277	protein coding gene	Chr13:20841876-20842366 (-)
BALB/cJ	MGP_BALBcJ_G0020293	protein coding gene	Chr13:20580460-20580850 (-)
C3H/HeJ	MGP_C3HHeJ_G0020101	protein coding gene	Chr13:20915572-20915962 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0020735	protein coding gene	Chr13:21736740-21737130 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018318	protein coding gene	Chr13:19393107-19393502 (-)
CAST/EiJ	MGP_CASTEiJ_G0019620	protein coding gene	Chr13:20605041-20605431 (-)
CBA/J	MGP_CBAJ_G0020052	protein coding gene	Chr13:22580150-22580540 (-)
DBA/2J	MGP_DBA2J_G0020177	protein coding gene	Chr13:20133031-20133421 (-)
FVB/NJ	MGP_FVBNJ_G0020164	protein coding gene	Chr13:19777537-19777927 (-)
LP/J	MGP_LPJ_G0020249	protein coding gene	Chr13:21294154-21294544 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020193	protein coding gene	Chr13:22889485-22889869 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020768	protein coding gene	Chr13:20692076-20692466 (-)
PWK/PhJ	MGP_PWKPhJ_G0019376	protein coding gene	Chr13:20159855-20160253 (-)
SPRET/EiJ	no annotation
WSB/EiJ	MGP_WSBEiJ_G0019676	protein coding gene	Chr13:20827869-20828259 (-)

Homology

• Human Ortholog
  H4C11, H4 clustered histone 11

• Vertebrate Orthologs
  16

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  H4C11, H4 clustered histone 11
  
• Synonyms
  dJ160A22.2, H4-16, H4C1, H4C12, H4C13, H4C14, H4C15, H4C16, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4/e, H4F2iv, H4FE, HIST1H4J, TEBIVANED2, TEVANED2
• Links
  HGNC:4785

  NCBI Gene ID: 8363

  neXtProt AC: NX_P62805

  UniProt: P62805

  
  
• Chr Location
  6p22.1; chr6:27824092-27824480 (+)  GRCh38

---

• Human Ortholog
  H4C5, H4 clustered histone 5
  
• Synonyms
  H4-16, H4C1, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, H4C2, H4C3, H4C4, H4C6, H4C8, H4C9, H4FJ, H4/j, HIST1H4E, TEBIVANED3, TEVANED3
• Links
  HGNC:4790

  NCBI Gene ID: 8367

  neXtProt AC: NX_P62805

  UniProt: P62805

  
  
• Chr Location
  6p22.2; chr6:26204610-26205021 (+)  GRCh38

---

• MGI Vertebrate Homology
  H4c6 stringent orthology
  2 human;1 mouse;4 rat;10 zebrafish
  
• HCOP
  vertebrate homology predictions: H4C11, H4C5
• Gene Tree
  H4c6
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  1
• Radiation induced
  1
• Targeted
  1
• Genomic Mutations
  2 involving H4c6
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  2 strains or lines available

Expression

• Assay Results
  737
• Tissues
  23
• cDNA Data
  3
• Literature Summary
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  27
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS26345.1

• Ensembl
  ENSMUSG00000069274 (Evidence)
• NCBI Gene
  319157

Representative Sequences			Length	Strain/Species
genomic	319157	NCBI Gene Model | MGI Sequence Detail	383	C57BL/6J
transcript	NM_175655	RefSeq | MGI Sequence Detail	383	C57BL/6
polypeptide	P62806	UniProt | EBI | MGI Sequence Detail	103	Not Applicable

Protein
Information

• UniProt
  1 Sequence

Molecular
Reagents

• All nucleic 5

  Genomic 1

  cDNA 3

  Primer pair 1

  
  

  Microarray probesets 1

Other
Accession IDs

MGI:6324985

References

• Summaries
  All 21

  Developmental Gene Expression 1

  Phenotypes 9
• Earliest
  J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
• Latest
  J:175731 Liu LJ, et al., Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development. Gene. 2011 Sep 1;483(1-2):1-10

TSS for H4c6:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr121715	Chr13:23735836-23735846 (-)	1 bp