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H4c16 Gene Detail
Summary
  • Symbol
    H4c16
  • Name
    H4 histone 16
  • Synonyms
    B130044J01Rik, H4-16, H4f16, Hist4h4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448443
    NCBI Gene: 320332
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:136780991-136781429 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 66.72 cM, cytoband G1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    134 from dbSNP Build 142
  • Strain Annotations
    8
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448443
 protein coding gene Chr6:136778551-136781429 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0031868
 protein coding gene Chr6:145138166-145142417 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0031088
 protein coding gene Chr6:150530468-150536100 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0031196
 protein coding gene Chr6:133437412-133441549 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0031236
 protein coding gene Chr6:154420238-154426596 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031900
 protein coding gene Chr6:139551928-139554189 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0030047
 protein coding gene Chr6:137807261-137811390 (-)
WSB/EiJ MGP_WSBEiJ_G0030589
 protein coding gene Chr6:140178641-140180864 (-)



Homology
more
  • Human Ortholog
    H4C16, H4 histone 16
  • Vertebrate Orthologs
    17
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H4C16, H4 histone 16
  • Synonyms
    H4-16, H4C1, H4C11, H4C12, H4C13, H4C14, H4C15, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4/p, HIST4H4
  • Links
    NCBI Gene ID: 121504
    neXtProt AC: NX_P62805
    UniProt: P62805

  • Chr Location
    12p12.3; chr12:14767999-14771131 (-)  GRCh38
  • Human Ortholog
    H4C2, H4 clustered histone 2
  • Synonyms
    H4-16, H4C1, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4FI, H4/I, HIST1H4B
  • Links
    NCBI Gene ID: 8366
    neXtProt AC: NX_P62805
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26026896-26027283 (-)  GRCh38
  • Human Ortholog
    H4C5, H4 clustered histone 5
  • Synonyms
    H4-16, H4C1, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, H4C2, H4C3, H4C4, H4C6, H4C8, H4C9, H4FJ, H4/j, HIST1H4E, TEBIVANED3, TEVANED3
  • Links
    NCBI Gene ID: 8367
    neXtProt AC: NX_P62805
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26204610-26205021 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    737
  • Tissues
    23
  • cDNA Data
    3
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 320332 NCBI Gene Model | MGI Sequence Detail 439 C57BL/6J ±  kb
    transcript NM_175652 RefSeq | MGI Sequence Detail 439 C57BL/6  
    polypeptide P62806 UniProt | EBI | MGI Sequence Detail 103 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • GlyGen
      P62806 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 5
      Genomic 1
      cDNA 3
      Primer pair 1

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:2443829, MGI:6325041, MGI:7285927
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 7
      Gene Ontology 1
      Phenotypes 6
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:346630 Zhang X, et al., Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature. Commun Biol. 2024 Mar 23;7(1):363
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    11/12/2024
    MGI 6.24     		The Jackson Laboratory