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Cyp2j7 Gene Detail
Summary
  • Symbol
    Cyp2j7
  • Name
    cytochrome P450, family 2, subfamily j, polypeptide 7
  • Synonyms
    Cyp2j7-ps, OTTMUSG00000007941
  • Feature Type
    protein coding gene
  • IDs
    MGI:2449816
    NCBI Gene: 546837
  • Member of
    Cyp2j cluster, Cyp2j cluster
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr4:96083434-96124896 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 44.35 cM
Strain
Comparison
more
  • SNPs within 2kb
    1000 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2449816
 protein coding gene Chr4:96082684-96124896 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028461
 protein coding gene Chr4:96299926-96336856 (-)
A/J MGP_AJ_G0028424
 protein coding gene Chr4:92904446-92940571 (-)
AKR/J MGP_AKRJ_G0028371
 protein coding gene Chr4:95167480-95208465 (-)
BALB/cJ MGP_BALBcJ_G0028442
 protein coding gene Chr4:93151387-93188136 (-)
C3H/HeJ MGP_C3HHeJ_G0028155
 protein coding gene Chr4:95956914-95990209 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028881
 protein coding gene Chr4:99944478-99984873 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026175
 protein coding gene Chr4:88391055-88423301 (-)
CAST/EiJ MGP_CASTEiJ_G0027595
 protein coding gene Chr4:93810703-93843375 (-)
CBA/J MGP_CBAJ_G0028124
 protein coding gene Chr4:102998094-103035629 (-)
DBA/2J MGP_DBA2J_G0028274
 protein coding gene Chr4:92694833-92732684 (-)
FVB/NJ MGP_FVBNJ_G0028241
 protein coding gene Chr4:91555834-91596519 (-)
LP/J MGP_LPJ_G0028374
 protein coding gene Chr4:96608704-96650048 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028269
 protein coding gene Chr4:108752940-108792499 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028919
 protein coding gene Chr4:95446491-95481734 (-)
PWK/PhJ MGP_PWKPhJ_G0027320
 protein coding gene Chr4:90838238-90873359 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027141
 protein coding gene Chr4:92833186-92870171 (-)
WSB/EiJ MGP_WSBEiJ_G0027673
 protein coding gene Chr4:95561092-95598136 (-)



Homology
more
  • Human Ortholog
    CYP2J2, cytochrome P450 family 2 subfamily J member 2
  • Vertebrate Orthologs
    14
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2J2, cytochrome P450 family 2 subfamily J member 2
  • Synonyms
    CPJ2, CYPIIJ2
  • Links
    NCBI Gene ID: 1573
    neXtProt AC: NX_P51589
    UniProt: P51589

  • Chr Location
    1p32.1; chr1:59893308-59969212 (-)  GRCh38
Human Diseases
more
  • Diseases
    5 with human CYP2J2 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    26
  • RefSeq
    2
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000081362 Ensembl Gene Model | MGI Sequence Detail 41463 C57BL/6J ±  kb
transcript ENSMUST00000162514 Ensembl | MGI Sequence Detail 1515 Not Applicable  
polypeptide ENSMUSP00000134331 Ensembl | MGI Sequence Detail 504 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001128 Cytochrome P450
    IPR017972 Cytochrome P450, conserved site
    IPR002401 Cytochrome P450, E-class, group I
    IPR008071 Cytochrome P450, E-class, group I, CYP2J-like
    IPR050182 Cytochrome P450 family 2
    IPR036396 Cytochrome P450 superfamily
Other
Accession IDs
less
MGI:3651265
References
more
  • Summaries
    All 15
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:223128 Zhou GL, et al., Deletion of the murine cytochrome P450 Cyp2j locus by fused BAC-mediated recombination identifies a role for Cyp2j in the pulmonary vascular response to hypoxia. PLoS Genet. 2013 Nov;9(11):e1003950
  • Latest
    J:261864 Beloiartsev A, et al., Pulmonary hypertension after prolonged hypoxic exposure in mice with a congenital deficiency of Cyp2j. Am J Respir Cell Mol Biol. 2015 May;52(5):563-70
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory