tth Gene Detail

Summary

• Symbol
  tth
• Name
  tremor with tilted head

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:2652743
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 15, Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  8 phenotypes from 2 alleles in 2 genetic backgrounds
  2 phenotype references
  

• All Mutations and Alleles
  2
• Spontaneous
  2
• Find Mice (IMSR)
  2 strains or lines available

By three weeks of age, homozygous mutant mice exhibit tremor when walking and lean and/or tilt their heads to one side. Hearing and inner ear morphology are normal. Males fail to breed despite having motile and morphologically normal sperm.

References

• Summaries
  All 2

  Phenotypes 2
• Earliest
  J:91623 Gagnon L, et al., A new spontaneous mutation resulting in body tremor and a tilited head. Mouse Mutant Resources Web Site, The Jackson Laboratory, Bar Harbor, Maine. MGI Direct Data Submission. 2004;
• Latest
  J:177024 Gagnon LH, et al., A second allele of tremor with tilted head. MGI Direct Data Submission. 2011;