Col23a1 MGI Mouse Gene Detail - MGI:2653243 - collagen, type XXIII, alpha 1

Symbol

Col23a1
Name

collagen, type XXIII, alpha 1
Synonyms

2810458L13Rik

Feature Type

protein coding gene
IDs

MGI:2653243
NCBI Gene: 237759
Alliance

gene page
Transcription Start Sites

4 TSS

Sequence Map

Chr11:51180747-51474745 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 31.03 cM
Mapping Data

3 experiments

SNPs within 2kb

8938 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2653243	protein coding gene	Chr11:51180508-51474752 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0018267	protein coding gene	Chr11:50513043-50831421 (+)
A/J	MGP_AJ_G0018236	protein coding gene	Chr11:48620328-48918219 (+)
AKR/J	MGP_AKRJ_G0018206	protein coding gene	Chr11:50146265-50454822 (+)
BALB/cJ	MGP_BALBcJ_G0018207	protein coding gene	Chr11:48921938-49214148 (+)
C3H/HeJ	MGP_C3HHeJ_G0018018	protein coding gene	Chr11:50185871-50479640 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0018657	protein coding gene	Chr11:52050548-52367594 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016309	protein coding gene	Chr11:46195409-46482872 (+)
CAST/EiJ	MGP_CASTEiJ_G0017582	protein coding gene	Chr11:50167618-50474818 (+)
CBA/J	MGP_CBAJ_G0017993	protein coding gene	Chr11:54496465-54822349 (+)
DBA/2J	MGP_DBA2J_G0018100	protein coding gene	Chr11:48335455-48627066 (+)
FVB/NJ	MGP_FVBNJ_G0018095	protein coding gene	Chr11:48031521-48331489 (+)
LP/J	MGP_LPJ_G0018176	protein coding gene	Chr11:50943638-51256262 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018118	protein coding gene	Chr11:55905300-56243924 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0018700	protein coding gene	Chr11:50238627-50552560 (+)
PWK/PhJ	MGP_PWKPhJ_G0017358	protein coding gene	Chr11:48840956-49146542 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0017153	protein coding gene	Chr11:49975542-50286161 (+)
WSB/EiJ	MGP_WSBEiJ_G0017630	protein coding gene	Chr11:49888416-50205108 (+)

Human Ortholog

COL23A1, collagen type XXIII alpha 1 chain

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

COL23A1, collagen type XXIII alpha 1 chain
Links

HGNC:22990

NCBI Gene ID: 91522

neXtProt AC: NX_Q86Y22

UniProt: Q86Y22
Chr Location

5q35.3; chr5:178237476-178590393 (-) GRCh38

MGI Vertebrate Homology

Col23a1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: COL23A1
Gene Tree

Col23a1

less

Phenotype Summary

7 phenotype references

All Mutations and Alleles

6
Chemically induced (other)

1
Endonuclease-mediated

2
Gene trapped

1
Targeted

2
Genomic Mutations

1 involving Col23a1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

19 strains or lines available

less

All GO Annotations

15
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

876
Tissues

117
cDNA Data

34
Literature Summary

12

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

less

All Sequences

40
RefSeq

7
UniProt

2
CCDS

CCDS24652.1

Ensembl

ENSMUSG00000063564 (Evidence)
NCBI Gene

237759

			Length	Strain/Species	Flank
genomic	ENSMUSG00000063564	Ensembl Gene Model \| MGI Sequence Detail	293999	C57BL/6J	± kb
transcript	ENSMUST00000102765	Ensembl \| MGI Sequence Detail	5658	Not Applicable
polypeptide	ENSMUSP00000099826	Ensembl \| MGI Sequence Detail	532	Not Applicable

less

UniProt

2 Sequences
Protein Ontology

PR:000005707 collagen alpha-1(XXIII) chain

(term hierarchy)
InterPro Domains

IPR050938 Collagen and Collagen-like Structural Proteins

IPR008160 Collagen triple helix repeat

less

All nucleic 41

Genomic 2

cDNA 36

Primer pair 3

Microarray probesets 6

less

MGI:1920044, MGI:2144160

Summaries

All 47

Developmental Gene Expression 12

Gene Ontology 5

Phenotypes 7
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:332240 Feng W, et al., Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stages. Nat Commun. 2022 Dec 27;13(1):7960

TSS for Col23a1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr101277	Chr11:51180565-51180581 (+)	-174 bp
Tssr101278	Chr11:51180795-51180838 (+)	70 bp
Tssr101279	Chr11:51275005-51275016 (+)	94,264 bp
Tssr101280	Chr11:51468715-51468721 (+)	287,971 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24