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Mptp1 QTL Detail
Summary
  • Symbol
    Mptp1
  • Name
    MPTP sensitivity 1
  • Feature Type
    QTL
  • IDs
    MGI:2656753
    NCBI Gene: 492911
Location &
Maps
more
  • Sequence Map
    Chr1:171632048-192681050 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, cM position of peak correlated region/marker: Syntenic
  • Mapping Data
    1 experiment
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Sequences &
Gene Models
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References
more
  • Summaries
    All 7
    Phenotypes 1
  • Earliest
    J:82236 Cook R, et al., Identification of a single QTL, Mptp1, for susceptibility to MPTP-induced substantia nigra pars compacta neuron loss in mice. Brain Res Mol Brain Res. 2003 Feb 20;110(2):279-88
  • Latest
    J:292037 Lindblom RSJ, et al., Delineating a role for the mitochondrial permeability transition pore in diabetic kidney disease by targeting cyclophilin D. Clin Sci (Lond). 2020 Jan 31;134(2):239-259
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory