Csnk1g1 MGI Mouse Gene Detail - MGI:2660884

Symbol

Csnk1g1
Name

casein kinase 1, gamma 1
Synonyms

9130020E21Rik

Feature Type

protein coding gene
IDs

MGI:2660884
NCBI Gene: 214897
Alliance

gene page
Transcription Start Sites

10 TSS

Sequence Map

Chr9:65816235-65952297 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 9, 35.60 cM
Mapping Data

2 experiments

SNPs within 2kb

2676 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2660884	protein coding gene	Chr9:65816206-65952297 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0034969	protein coding gene	Chr9:65707911-65846902 (+)
A/J	MGP_AJ_G0034949	protein coding gene	Chr9:63462528-63591390 (+)
AKR/J	MGP_AKRJ_G0034879	protein coding gene	Chr9:64975884-65108002 (+)
BALB/cJ	MGP_BALBcJ_G0034942	protein coding gene	Chr9:63178181-63307593 (+)
C3H/HeJ	MGP_C3HHeJ_G0034652	protein coding gene	Chr9:65503871-65638056 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0035461	protein coding gene	Chr9:67486994-67630181 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0032372	protein coding gene	Chr9:63110277-63240917 (+)
CAST/EiJ	MGP_CASTEiJ_G0033973	protein coding gene	Chr9:65694511-65831140 (+)
CBA/J	MGP_CBAJ_G0034623	protein coding gene	Chr9:69842465-69980360 (+)
DBA/2J	MGP_DBA2J_G0034782	protein coding gene	Chr9:63235297-63368353 (+)
FVB/NJ	MGP_FVBNJ_G0034724	protein coding gene	Chr9:62571750-62710862 (+)
LP/J	MGP_LPJ_G0034865	protein coding gene	Chr9:65947531-66089108 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0034766	protein coding gene	Chr9:71093649-71232413 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0035483	protein coding gene	Chr9:65086410-65216013 (+)
PWK/PhJ	MGP_PWKPhJ_G0033677	protein coding gene	Chr9:63434358-63566402 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0033511	protein coding gene	Chr9:65358823-65505791 (+)
WSB/EiJ	MGP_WSBEiJ_G0034086	protein coding gene	Chr9:64974616-65115593 (+)

Human Ortholog

CSNK1G1, casein kinase 1 gamma 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CSNK1G1, casein kinase 1 gamma 1
Synonyms

CK1gamma1
Links

HGNC:2454

NCBI Gene ID: 53944

neXtProt AC: NX_Q9HCP0

UniProt: Q9HCP0
Chr Location

15q22.31; chr15:64165525-64356173 (-) GRCh38

MGI Vertebrate Homology

Csnk1g1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: CSNK1G1
Gene Tree

Csnk1g1

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Phenotype Summary

6 phenotypes from 1 allele in 1 genetic background
13 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

35
Chemically induced (other)

1
Endonuclease-mediated

1
Gene trapped

31
Targeted

2
Genomic Mutations

1 involving Csnk1g1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

45 strains or lines available

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All GO Annotations

35
GO References

8

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

804
Tissues

68
cDNA Data

85
Literature Summary

4

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GENSAT

GEO

Expression Atlas
Other Vertebrate Links

Xenbase csnk1g1

ZFIN csnk1g1

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All Sequences

103
RefSeq

29
UniProt

12
CCDS

CCDS23300.1

Ensembl

ENSMUSG00000032384 (Evidence)
NCBI Gene

214897

			Length	Strain/Species	Flank
genomic	214897	NCBI Gene Model \| MGI Sequence Detail	136063	C57BL/6J	± kb
transcript	NM_173185	RefSeq \| MGI Sequence Detail	7217	C57BL/6
polypeptide	Q8BTH8	UniProt \| EBI \| MGI Sequence Detail	459	Not Applicable

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UniProt

12 Sequences
Protein Ontology

PR:000005947 casein kinase I isoform gamma-1

(term hierarchy)
EC

2.7.11.1
InterPro Domains

IPR022247 Casein kinase 1 gamma C-terminal

IPR050235 Casein Kinase 1 Ser/Thr Protein Kinase

IPR017441 Protein kinase, ATP binding site

IPR000719 Protein kinase domain

IPR011009 Protein kinase-like domain superfamily

IPR008271 Serine/threonine-protein kinase, active site
GlyGen

Q8BTH8 1 site, 1 N-linked glycan (1 site)

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All nucleic 87

cDNA 86

Primer pair 1

Microarray probesets 3

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MGI:1918866

Summaries

All 46

Developmental Gene Expression 4

Gene Ontology 8

Phenotypes 13
Earliest

J:14749 Fujimoto S, et al., Nucleotide sequence of a cDNA encoding an alternative form of LEF-1. Nucleic Acids Res. 1993 Sep 11;21(18):4403
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Csnk1g1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr85733	Chr9:65816249-65816301 (+)	40 bp
Tssr85734	Chr9:65816305-65816365 (+)	100 bp
Tssr85735	Chr9:65816372-65816383 (+)	143 bp
Tssr85736	Chr9:65821612-65821613 (+)	5,378 bp
Tssr85737	Chr9:65831460-65831480 (+)	15,235 bp
Tssr85738	Chr9:65831489-65831498 (+)	15,259 bp
Tssr85739	Chr9:65873219-65873222 (+)	56,986 bp
Tssr85740	Chr9:65911936-65911970 (+)	95,718 bp
Tssr85741	Chr9:65939789-65939793 (+)	123,556 bp
Tssr85742	Chr9:65947754-65947781 (+)	131,533 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24