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Actr3b Gene Detail
Summary
  • Symbol
    Actr3b
  • Name
    ARP3 actin-related protein 3B
  • Synonyms
    ARP11, Arp3b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2661120
    NCBI Gene: 242894
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:25964995-26055686 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 12.35 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3200 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2661120
 protein coding gene Chr5:25964960-26055686 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029364
 protein coding gene Chr5:23589687-23689940 (+)
A/J MGP_AJ_G0029330
 protein coding gene Chr5:22746060-22835141 (+)
AKR/J MGP_AKRJ_G0029281
 protein coding gene Chr5:23686100-23780535 (+)
BALB/cJ MGP_BALBcJ_G0029341
 protein coding gene Chr5:23259098-23347641 (+)
C3H/HeJ MGP_C3HHeJ_G0029061
 protein coding gene Chr5:23779741-23875334 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029794
 protein coding gene Chr5:25116737-25219215 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027032
 protein coding gene Chr5:20659306-20677504 (+)
CAST/EiJ MGP_CASTEiJ_G0028473
 protein coding gene Chr5:22995165-23093921 (+)
CBA/J MGP_CBAJ_G0029028
 protein coding gene Chr5:25576676-25679511 (+)
DBA/2J MGP_DBA2J_G0029179
 protein coding gene Chr5:23015470-23108696 (+)
FVB/NJ MGP_FVBNJ_G0029137
 protein coding gene Chr5:22400165-22489910 (+)
LP/J MGP_LPJ_G0029263
 protein coding gene Chr5:23982338-24083084 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029166
 protein coding gene Chr5:26630567-26732099 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029828
 protein coding gene Chr5:23298291-23389195 (+)
PWK/PhJ MGP_PWKPhJ_G0028197
 protein coding gene Chr5:22150446-22246485 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028028
 protein coding gene Chr5:22653302-22752168 (+)
WSB/EiJ MGP_WSBEiJ_G0028553
 protein coding gene Chr5:23385706-23481587 (+)



Homology
more
  • Human Ortholog
    ACTR3B, actin related protein 3B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACTR3B, actin related protein 3B
  • Synonyms
    ARP11, ARP3BETA
  • Links
    NCBI Gene ID: 57180
    neXtProt AC: NX_Q9P1U1
    UniProt: Q9P1U1

  • Chr Location
    7q36.1-q36.2; chr7:152759749-152855378 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    737
  • Tissues
    5
  • cDNA Data
    11
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000056367 Ensembl Gene Model | MGI Sequence Detail 90692 C57BL/6J ±  kb
transcript ENSMUST00000088244 Ensembl | MGI Sequence Detail 1712 Not Applicable  
polypeptide ENSMUSP00000085578 Ensembl | MGI Sequence Detail 418 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141129
References
more
  • Summaries
    All 42
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 3
    Phenotypes 15
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory