nmf148 Gene Detail

Summary

• Symbol
  nmf148
• Name
  neuroscience mutagenesis facility, 148

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:2663828
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr11:98574481-109219301 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 1 allele in 1 genetic background
  4 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (ENU)
  1
• Targeted
  2
• Genomic Mutations
  2 involving nmf148
• Find Mice (IMSR)
  1 strains or lines available

Mice homozygous for an ENU-induced mutation are small and display an unsteady gait at approximately 3-4 weeks of age.

References

• Summaries
  All 5

  Phenotypes 4
• Earliest
  J:50799 Liu P, et al., Embryonic lethality and tumorigenesis caused by segmental aneuploidy on mouse chromosome 11. Genetics. 1998 Nov;150(3):1155-68
• Latest
  J:232020 Ermakova O, et al., Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice. EMBO Mol Med. 2011 Jan;3(1):50-66