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Serpinb6e Gene Detail
Summary
  • Symbol
    Serpinb6e
  • Name
    serine (or cysteine) peptidase inhibitor, clade B, member 6e
  • Synonyms
    Gm11396, ovalbumin, SPI3B
  • Feature Type
    protein coding gene
  • IDs
    MGI:2667778
    NCBI Gene: 435350
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:34016328-34027391 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 13.98 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    420 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2667778
 protein coding gene Chr13:34016328-34027391 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020441
 protein coding gene Chr13:31944445-31955492 (-)
A/J MGP_AJ_G0020396
 protein coding gene Chr13:31004820-31015847 (-)
AKR/J MGP_AKRJ_G0020373
 protein coding gene Chr13:31721323-31732332 (-)
BALB/cJ MGP_BALBcJ_G0020391
 protein coding gene Chr13:31080895-31091906 (-)
C3H/HeJ MGP_C3HHeJ_G0020190
 protein coding gene Chr13:31660981-31671992 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020825
 protein coding gene Chr13:32992522-33005580 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018412
 protein coding gene Chr13:29064819-29081349 (-)
CAST/EiJ MGP_CASTEiJ_G0019706
 protein coding gene Chr13:31317963-31329005 (-)
CBA/J MGP_CBAJ_G0020150
 protein coding gene Chr13:34432373-34443386 (-)
DBA/2J MGP_DBA2J_G0020272
 protein coding gene Chr13:30522233-30533238 (-)
FVB/NJ MGP_FVBNJ_G0020252
 protein coding gene Chr13:30100982-30112028 (-)
LP/J MGP_LPJ_G0020348
 protein coding gene Chr13:32163030-32174039 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020283
 protein coding gene Chr13:34659205-34670260 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020868
 protein coding gene Chr13:31385237-31396248 (-)
PWK/PhJ MGP_PWKPhJ_G0019461
 protein coding gene Chr13:30645428-30656968 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019286
 protein coding gene Chr13:30049326-30060777 (-)
WSB/EiJ MGP_WSBEiJ_G0019768
 protein coding gene Chr13:31744679-31755685 (-)



Homology
more
  • Human Ortholog
    SERPINB6, serpin family B member 6
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SERPINB6, serpin family B member 6
  • Synonyms
    CAP, DFNB91, MSTP057, PI-6, PI6, PTI, SPI3
  • Links
    NCBI Gene ID: 5269
    neXtProt AC: NX_P35237
    UniProt: P35237

  • Chr Location
    6p25.2; chr6:2948159-2972165 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SERPINB6 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    4
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 435350 NCBI Gene Model | MGI Sequence Detail 11064 C57BL/6J ±  kb
transcript NM_001045535 RefSeq | MGI Sequence Detail 1494 Not Specified  
polypeptide NP_001039000 RefSeq | MGI Sequence Detail 429 Not Specified  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    Genomic 1
    Primer pair 1
    Other 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:3651663
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory