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Ms4a5 Gene Detail
Summary
  • Symbol
    Ms4a5
  • Name
    membrane-spanning 4-domains, subfamily A, member 5
  • Synonyms
    MGC:58438
  • Feature Type
    protein coding gene
  • IDs
    MGI:2670985
    NCBI Gene: 269063
  • Member of
    Ms4ac cluster
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:11251514-11261259 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 8.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    329 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2670985
 protein coding gene Chr19:11250602-11261259 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024874
 protein coding gene Chr19:8651984-8663183 (-)
A/J MGP_AJ_G0024842
 protein coding gene Chr19:8094232-8105404 (-)
AKR/J MGP_AKRJ_G0024817
 protein coding gene Chr19:8389635-8401010 (-)
BALB/cJ MGP_BALBcJ_G0024842
 protein coding gene Chr19:8127880-8139920 (-)
C3H/HeJ MGP_C3HHeJ_G0024608
 protein coding gene Chr19:8283124-8294323 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025290
 protein coding gene Chr19:9047092-9058269 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022717
 protein coding gene Chr19:8497827-8511501 (-)
CAST/EiJ MGP_CASTEiJ_G0024081
 protein coding gene Chr19:7920642-7933873 (-)
CBA/J MGP_CBAJ_G0024582
 protein coding gene Chr19:9096586-9109558 (-)
DBA/2J MGP_DBA2J_G0024709
 protein coding gene Chr19:8088395-8099690 (-)
FVB/NJ MGP_FVBNJ_G0024676
 protein coding gene Chr19:8115055-8126209 (-)
LP/J MGP_LPJ_G0024796
 protein coding gene Chr19:8610377-8621576 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024703
 protein coding gene Chr19:8982585-8997756 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025338
 protein coding gene Chr19:8422455-8438778 (-)
PWK/PhJ MGP_PWKPhJ_G0023825
 protein coding gene Chr19:7527928-7539648 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023631
 protein coding gene Chr19:7614993-7625956 (-)
WSB/EiJ MGP_WSBEiJ_G0024143
 protein coding gene Chr19:8322014-8333196 (-)



Homology
more
  • Human Ortholog
    MS4A5, membrane spanning 4-domains A5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MS4A5, membrane spanning 4-domains A5
  • Synonyms
    CD20-L2, CD20L2, TETM4
  • Links
    NCBI Gene ID: 64232
    neXtProt AC: NX_Q9H3V2
    UniProt: Q9H3V2

  • Chr Location
    11q12.2; chr11:60429572-60455214 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    15
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 269063 NCBI Gene Model | MGI Sequence Detail 9746 C57BL/6J ±  kb
transcript NM_183190 RefSeq | MGI Sequence Detail 721 C57BL/6  
polypeptide NP_899013 RefSeq | MGI Sequence Detail 197 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR007237 CD20-like family
    IPR030417 Membrane-spanning 4-domains subfamily A
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 1
References
more
  • Summaries
    All 17
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory