About   Help   FAQ
Scd4 Gene Detail
Summary
  • Symbol
    Scd4
  • Name
    stearoyl-coenzyme A desaturase 4
  • Synonyms
    MGC:48154
  • Feature Type
    protein coding gene
  • IDs
    MGI:2670997
    NCBI Gene: 329065
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:44321765-44335182 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 37.98 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    517 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2670997
 protein coding gene Chr19:44321531-44335182 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025169
 protein coding gene Chr19:43800821-43816510 (+)
A/J MGP_AJ_G0025146
 protein coding gene Chr19:41712721-41726183 (+)
AKR/J MGP_AKRJ_G0025114
 protein coding gene Chr19:43031999-43047480 (+)
BALB/cJ MGP_BALBcJ_G0025140
 protein coding gene Chr19:41762614-41776491 (+)
C3H/HeJ MGP_C3HHeJ_G0024900
 protein coding gene Chr19:43210027-43224601 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025583
 protein coding gene Chr19:44882795-44897823 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022997
 protein coding gene Chr19:40993722-41005656 (+)
CAST/EiJ MGP_CASTEiJ_G0024365
 protein coding gene Chr19:42912221-42928106 (+)
CBA/J MGP_CBAJ_G0024880
 protein coding gene Chr19:47125988-47145601 (+)
DBA/2J MGP_DBA2J_G0025012
 protein coding gene Chr19:41529072-41543334 (+)
FVB/NJ MGP_FVBNJ_G0024973
 protein coding gene Chr19:41297444-41315272 (+)
LP/J MGP_LPJ_G0025098
 protein coding gene Chr19:43749711-43761686 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025004
 protein coding gene Chr19:46597998-46611335 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025641
 protein coding gene Chr19:43115385-43129824 (+)
PWK/PhJ MGP_PWKPhJ_G0024114
 protein coding gene Chr19:41428755-41442977 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023918
 protein coding gene Chr19:41826750-41841292 (+)
WSB/EiJ MGP_WSBEiJ_G0024435
 protein coding gene Chr19:43247361-43263311 (+)



Homology
more
  • Human Ortholog
    SCD, stearoyl-CoA desaturase
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCD, stearoyl-CoA desaturase
  • Synonyms
    FADS5, hSCD1, MSTP008, SCD1, SCDOS
  • Links
    NCBI Gene ID: 6319
    neXtProt AC: NX_O00767
    UniProt: O00767

  • Chr Location
    10q24.31; chr10:100347233-100364826 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    3
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 329065 NCBI Gene Model | MGI Sequence Detail 13418 C57BL/6J ±  kb
transcript NM_183216 RefSeq | MGI Sequence Detail 3072 C57BL/6  
polypeptide Q6T707 UniProt | EBI | MGI Sequence Detail 353 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 27
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:85276 Miyazaki M, et al., Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors. J Biol Chem. 2003 Sep 5;278(36):33904-11
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory