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Lncpint Gene Detail
Summary
  • Symbol
    Lncpint
  • Name
    long non-protein coding RNA, Trp53 induced transcript
  • Synonyms
    AB041803, Lincpint, Linc-Pint, MNCb-1768, Pint
  • Feature Type
    lncRNA gene
  • IDs
    MGI:2673128
    NCBI Gene: 232685
  • Alliance
    gene page
  • Transcription Start Sites
    25 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:31070498-31195409 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 12.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3150 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2673128
 lncRNA gene Chr6:31059500-31197423 (-)
129S1/SvImJ MGP_129S1SvImJ_G0006921
 lincRNA gene Chr6:28999134-29124818 (-)
A/J MGP_AJ_G0006915
 lincRNA gene Chr6:27774900-27899111 (-)
AKR/J MGP_AKRJ_G0006885
 lincRNA gene Chr6:28704109-28828550 (-)
BALB/cJ MGP_BALBcJ_G0006891
 lincRNA gene Chr6:27895941-28021851 (-)
C3H/HeJ MGP_C3HHeJ_G0006836
 lincRNA gene Chr6:28714187-28841488 (-)
C57BL/6NJ MGP_C57BL6NJ_G0007056
 lincRNA gene Chr6:29817144-29951226 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0006304
 lincRNA gene Chr6:25937015-26060423 (-)
CAST/EiJ MGP_CASTEiJ_G0006753
 lincRNA gene Chr6:28488635-28617057 (-)
CBA/J MGP_CBAJ_G0006818
 lincRNA gene Chr6:30996657-31123806 (-)
DBA/2J MGP_DBA2J_G0006838
 lincRNA gene Chr6:27671528-27797066 (-)
FVB/NJ MGP_FVBNJ_G0006861
 lincRNA gene Chr6:27466450-27592224 (-)
LP/J MGP_LPJ_G0006921
 lincRNA gene Chr6:29186933-29317439 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0006842
 lincRNA gene Chr6:33385668-33515441 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0007058
 lincRNA gene Chr6:28593882-28723936 (-)
PWK/PhJ MGP_PWKPhJ_G0006695
 lincRNA gene Chr6:27247628-27374267 (-)
SPRET/EiJ MGP_SPRETEiJ_G0006604
 lincRNA gene Chr6:28282627-28409084 (-)
WSB/EiJ MGP_WSBEiJ_G0006808
 lincRNA gene Chr6:28517596-28646652 (-)



Homology
more
  • Human Ortholog
    LINC-PINT, long intergenic non-protein coding RNA, p53 induced transcript
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LINC-PINT, long intergenic non-protein coding RNA, p53 induced transcript
  • Synonyms
    LincRNA-Pint, MKLN1-AS1, PINT, PINT87aa, TISPL
  • Links
    NCBI Gene ID: 378805

  • Chr Location
    7q32.3; chr7:130791264-131110176 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotypes from 1 allele in 2 genetic backgrounds
    1 images
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display decreased body weight. Mice homozygous for a different null allele show premature aging phenotypes including progressive fur loss and muscle weakness, lordokyphosis, reduced body fat and bone mineral density, a slower growth rate, and reduced survival.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      48
    • RefSeq
      3
    • UniProt
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 232685 NCBI Gene Model | MGI Sequence Detail 124912 C57BL/6J ±  kb
    transcript NR_110469 RefSeq | MGI Sequence Detail 1714 C57BL/6  
    polypeptide Q8K5E3 UniProt | EBI | MGI Sequence Detail 96 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    Molecular
    Reagents
    less
    • All nucleic 2
      Genomic 1
      cDNA 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 20
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 6
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:285983 Simchovitz A, et al., A lncRNA survey finds increases in neuroprotective LINC-PINT in Parkinson's disease substantia nigra. Aging Cell. 2020 Mar;19(3):e13115
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory