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Tmem60 Gene Detail
Summary
  • Symbol
    Tmem60
  • Name
    transmembrane protein 60
  • Synonyms
    MGC:38035
  • Feature Type
    protein coding gene
  • IDs
    MGI:2673965
    NCBI Gene: 212090
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:21087451-21091868 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 9.83 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    188 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2673965
 protein coding gene Chr5:21087189-21091868 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029311
 protein coding gene Chr5:18397070-18401749 (+)
A/J MGP_AJ_G0029276
 protein coding gene Chr5:17824096-17828775 (+)
AKR/J MGP_AKRJ_G0029227
 protein coding gene Chr5:18501120-18505801 (+)
BALB/cJ MGP_BALBcJ_G0029288
 protein coding gene Chr5:18251352-18256031 (+)
C3H/HeJ MGP_C3HHeJ_G0029007
 protein coding gene Chr5:18534440-18539119 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029741
 protein coding gene Chr5:19771045-19775724 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026980
 protein coding gene Chr5:15892798-15897179 (+)
CAST/EiJ MGP_CASTEiJ_G0028419
 protein coding gene Chr5:17887195-17891882 (+)
CBA/J MGP_CBAJ_G0028974
 protein coding gene Chr5:19987033-19991712 (+)
DBA/2J MGP_DBA2J_G0029126
 protein coding gene Chr5:18099029-18103708 (+)
FVB/NJ MGP_FVBNJ_G0029084
 protein coding gene Chr5:17514185-17518864 (+)
LP/J MGP_LPJ_G0029210
 protein coding gene Chr5:18814858-18819537 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029112
 protein coding gene Chr5:21304829-21309508 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029774
 protein coding gene Chr5:18161146-18165826 (+)
PWK/PhJ MGP_PWKPhJ_G0028142
 protein coding gene Chr5:17168328-17173086 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027975
 protein coding gene Chr5:17527699-17532398 (+)
WSB/EiJ MGP_WSBEiJ_G0028499
 protein coding gene Chr5:18197097-18201777 (+)



Homology
more
  • Human Ortholog
    TMEM60, transmembrane protein 60
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM60, transmembrane protein 60
  • Synonyms
    C7orf35, DC32
  • Links
    NCBI Gene ID: 85025
    neXtProt AC: NX_Q9H2L4
    UniProt: Q9H2L4

  • Chr Location
    7q11.23; chr7:77793728-77798434 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 212090 NCBI Gene Model | MGI Sequence Detail 4418 C57BL/6J ±  kb
    transcript NM_177601 RefSeq | MGI Sequence Detail 899 C57BL/6  
    polypeptide Q8K174 UniProt | EBI | MGI Sequence Detail 133 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 2
    References
    more
    • Summaries
      All 35
      Diseases 1
      Gene Ontology 1
      Phenotypes 18
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory