Mir132 MGI Mouse Gene Detail - MGI:2676817

Symbol

Mir132
Name

microRNA 132
Synonyms

Mirn132, mmu-mir-132

Feature Type

miRNA gene
IDs

MGI:2676817
NCBI Gene: 387150
Member of

Mirc19 cluster
Alliance

gene page

Sequence Map

Chr11:75064508-75064573 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 45.76 cM
Mapping Data

1 experiment

SNPs within 2kb

60 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2676817	miRNA gene	Chr11:75064508-75064573 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0007840	miRNA gene	Chr11:75905293-75905358 (+)
A/J	MGP_AJ_G0007835	miRNA gene	Chr11:73086238-73086303 (+)
AKR/J	MGP_AKRJ_G0007810	miRNA gene	Chr11:75301138-75301203 (+)
BALB/cJ	MGP_BALBcJ_G0007813	miRNA gene	Chr11:73456925-73456990 (+)
C3H/HeJ	MGP_C3HHeJ_G0007760	miRNA gene	Chr11:75314250-75314315 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0007991	miRNA gene	Chr11:78280137-78280202 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007135	miRNA gene	Chr11:70102758-70102823 (+)
CAST/EiJ	MGP_CASTEiJ_G0007653	miRNA gene	Chr11:75702550-75702615 (+)
CBA/J	MGP_CBAJ_G0007731	miRNA gene	Chr11:81717314-81717379 (+)
DBA/2J	MGP_DBA2J_G0007766	miRNA gene	Chr11:72692210-72692275 (+)
FVB/NJ	MGP_FVBNJ_G0007784	miRNA gene	Chr11:72253520-72253585 (+)
LP/J	MGP_LPJ_G0007844	miRNA gene	Chr11:76498094-76498159 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0007754	miRNA gene	Chr11:82303576-82303641 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0007988	miRNA gene	Chr11:75486824-75486889 (+)
PWK/PhJ	MGP_PWKPhJ_G0007581	miRNA gene	Chr11:73388533-73388598 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0007476	miRNA gene	Chr11:75057896-75057961 (+)
WSB/EiJ	MGP_WSBEiJ_G0007721	miRNA gene	Chr11:75305808-75305873 (+)

Human Ortholog

MIR132, microRNA 132

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR132, microRNA 132
Synonyms

mir-132, MIRN132, miRNA132
Links

HGNC:31516

NCBI Gene ID: 406921
Chr Location

chr17:2049908-2050008 (-) GRCh38

MGI Vertebrate Homology

Mir132 stringent orthology
1 human;1 mouse;1 zebrafish
HCOP

vertebrate homology predictions: MIR132
Gene Tree

Mir132

Diseases

1 with human MIR132 associations

				Human Disease	Mouse Models
				nasopharynx carcinoma IDs nasopharynx carcinoma DOID:9261 DOID:8813 DOID:8814 DOID:9057 DOID:9144 DOID:9197 DOID:9229 ICD10CM:C11 ICD10CM:C11.0 ICD10CM:C11.1 ICD10CM:C11.2 ICD10CM:C11.3 ICD9CM:147 ICD9CM:147.0 ICD9CM:147.1 ICD9CM:147.2 ICD9CM:147.3 ICD9CM:147.9 MESH:D009303 NCI:C9321 OMIM:161550 OMIM:607107 ORDO:150 UMLS_CUI:C0153392 UMLS_CUI:C0153393 UMLS_CUI:C0153394 UMLS_CUI:C0153395 UMLS_CUI:C0153396 UMLS_CUI:C0238301

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

9 phenotype references

All Mutations and Alleles

3
Chemically induced (other)

1
Targeted

2
Genomic Mutations

3 involving Mir132
Find Mice (IMSR)

0 strains or lines available

Mice homozygous for an allele lacking both Mir212 and Mir132 exhibit disrupted cortical synaptic transmission and plasticity. Mice homozygous for another knock-out allele exhibit abnormal mammary gland development (see Mirc19).

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All GO Annotations

7
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

739
Tissues

11
Literature Summary

10

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

24
RefSeq

1

Ensembl

ENSMUSG00000065537 (Evidence)
NCBI Gene

387150

Representative Sequences				Length	Strain/Species	Flank
	genomic	387150	NCBI Gene Model \| MGI Sequence Detail	66	C57BL/6J	± kb
	transcript	NR_029546	RefSeq \| MGI Sequence Detail	66	C57BL/6

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All nucleic 4

Primer pair 2

Other 2

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miRBase

MI0000158

Summaries

All 86

Developmental Gene Expression 10

Gene Ontology 6

Phenotypes 9
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:344338 Subramanian M, et al., Growth-suppressor microRNAs mediate synaptic overgrowth and behavioral deficits in Fragile X mental retardation protein deficiency. iScience. 2024 Jan 19;27(1):108676

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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