Mir136 MGI Mouse Gene Detail - MGI:2676821

Symbol

Mir136
Name

microRNA 136
Synonyms

Mirn136, mmu-mir-136

Feature Type

miRNA gene
IDs

MGI:2676821
NCBI Gene: 387154
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr12:109561761-109561822 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 12, 60.39 cM
Mapping Data

1 experiment

SNPs within 2kb

7 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2676821	miRNA gene	Chr12:109561761-109561822 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0007973	miRNA gene	Chr12:111825351-111825412 (+)
A/J	MGP_AJ_G0007967	miRNA gene	Chr12:107518132-107518193 (+)
AKR/J	MGP_AKRJ_G0007944	miRNA gene	Chr12:110655475-110655536 (+)
BALB/cJ	MGP_BALBcJ_G0007946	miRNA gene	Chr12:107991677-107991738 (+)
C3H/HeJ	MGP_C3HHeJ_G0007892	miRNA gene	Chr12:111097983-111098044 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0008127	miRNA gene	Chr12:115243267-115243328 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007254	miRNA gene	Chr12:104045111-104045172 (+)
CAST/EiJ	MGP_CASTEiJ_G0007780	miRNA gene	Chr12:106048122-106048183 (+)
CBA/J	MGP_CBAJ_G0007862	miRNA gene	Chr12:119782657-119782718 (+)
DBA/2J	MGP_DBA2J_G0007897	miRNA gene	Chr12:107073222-107073283 (+)
FVB/NJ	MGP_FVBNJ_G0007916	miRNA gene	Chr12:105863891-105863952 (+)
LP/J	MGP_LPJ_G0007978	miRNA gene	Chr12:111652829-111652890 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0007887	miRNA gene	Chr12:122939337-122939398 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0008122	miRNA gene	Chr12:110137042-110137103 (+)
PWK/PhJ	MGP_PWKPhJ_G0007702	miRNA gene	Chr12:101681729-101681790 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0007599	miRNA gene	Chr12:104306889-104306950 (+)
WSB/EiJ	MGP_WSBEiJ_G0007849	miRNA gene	Chr12:111049924-111049985 (+)

Human Ortholog

MIR136, microRNA 136

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR136, microRNA 136
Synonyms

mir-136, MIRN136, miRNA136
Links

HGNC:31522

NCBI Gene ID: 406927
Chr Location

chr14:100884702-100884783 (+) GRCh38

MGI Vertebrate Homology

Mir136 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR136
Gene Tree

Mir136

Diseases

3 with human MIR136 associations

				Human Disease	Mouse Models
				colorectal cancer IDs colorectal cancer DOID:9256 ICD10CM:C18.9 KEGG:05210 MESH:D015179 NCI:C2956 NCI:C4978 OMIM:114500 UMLS_CUI:C0009404 UMLS_CUI:C0346629
				lung cancer IDs lung cancer DOID:1324 DOID:13075 DOID:1322 DOID:9881 ICD10CM:C34.1 ICD10CM:C34.2 ICD10CM:C34.3 ICD9CM:162.3 ICD9CM:162.4 ICD9CM:162.5 ICD9CM:162.8 OMIM:211980 OMIM:608935 OMIM:612571 OMIM:612593 OMIM:614210 UMLS_CUI:C0024624 UMLS_CUI:C0153491 UMLS_CUI:C0153492 UMLS_CUI:C0153493
				lung non-small cell carcinoma IDs lung non-small cell carcinoma DOID:3908 EFO:0003060 KEGG:05223 MESH:D002289 NCI:C2926 UMLS_CUI:C0007131

Click on a disease name to see all genes associated with that disease.

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All GO Annotations

1
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

718
Tissues

3
Literature Summary

9

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

24
RefSeq

1

Ensembl

ENSMUSG00000104858 (Evidence)
NCBI Gene

387154

Representative Sequences				Length	Strain/Species	Flank
	genomic	387154	NCBI Gene Model \| MGI Sequence Detail	62	C57BL/6J	± kb
	transcript	NR_029550	RefSeq \| MGI Sequence Detail	62	C57BL/6

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All nucleic 2

Primer pair 1

Other 1

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miRBase

MI0000162

Summaries

All 18

Developmental Gene Expression 9

Gene Ontology 1
Earliest

J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
Latest

J:316109 Lippi G, et al., MicroRNA-101 Regulates Multiple Developmental Programs to Constrain Excitation in Adult Neural Networks. Neuron. 2016 Dec 21;92(6):1337-1351

TSS for Mir136:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr115135	Chr12:109561821-109561825 (+)	62 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24