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Mir182 Gene Detail
Summary
  • Symbol
    Mir182
  • Name
    microRNA 182
  • Synonyms
    Mirn182, mmu-mir-182
Location &
Maps
more
  • Sequence Map
    Chr6:30165917-30165991 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 12.52 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    105 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676846
 miRNA gene Chr6:30165917-30165991 (-)
129S1/SvImJ MGP_129S1SvImJ_G0008888
 miRNA gene Chr6:28017359-28017433 (-)
A/J MGP_AJ_G0008873
 miRNA gene Chr6:26820952-26821026 (-)
AKR/J MGP_AKRJ_G0008863
 miRNA gene Chr6:27705977-27706051 (-)
BALB/cJ MGP_BALBcJ_G0008861
 miRNA gene Chr6:26978484-26978558 (-)
C3H/HeJ MGP_C3HHeJ_G0008800
 miRNA gene Chr6:27708160-27708234 (-)
C57BL/6NJ MGP_C57BL6NJ_G0009090
 miRNA gene Chr6:28829290-28829364 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0008011
 miRNA gene Chr6:25029298-25029372 (-)
CAST/EiJ MGP_CASTEiJ_G0008643
 miRNA gene Chr6:27519940-27520014 (-)
CBA/J MGP_CBAJ_G0008767
 miRNA gene Chr6:29904502-29904576 (-)
DBA/2J MGP_DBA2J_G0008799
 miRNA gene Chr6:26758556-26758630 (-)
FVB/NJ MGP_FVBNJ_G0008817
 miRNA gene Chr6:26519799-26519873 (-)
LP/J MGP_LPJ_G0008892
 miRNA gene Chr6:28154539-28154613 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0008783
 miRNA gene Chr6:32380166-32380240 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0009067
 miRNA gene Chr6:27594363-27594437 (-)
PWK/PhJ MGP_PWKPhJ_G0008570
 miRNA gene Chr6:26319744-26319818 (-)
SPRET/EiJ MGP_SPRETEiJ_G0008415
 miRNA gene Chr6:27328227-27328301 (-)
WSB/EiJ MGP_WSBEiJ_G0008739
 miRNA gene Chr6:27564818-27564892 (-)



Homology
more
  • Human Ortholog
    MIR182, microRNA 182
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR182, microRNA 182
  • Synonyms
    mir-182, MIRN182, miRNA182
  • Links
    NCBI Gene ID: 406958

  • Chr Location
    chr7:129770383-129770492 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 3 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    14 phenotype references
Mcie homozygous for a knock-out allele exhibit normal retinal morphology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    916
  • Tissues
    92
  • Literature Summary
    25
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 387177 NCBI Gene Model | MGI Sequence Detail 75 C57BL/6J ±  kb
transcript NR_029569 RefSeq | MGI Sequence Detail 75 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 20
    Primer pair 10
    Other 10
Other Database
Links
less
miRBase MI0000224
References
more
  • Summaries
    All 77
    Developmental Gene Expression 25
    Gene Ontology 7
    Phenotypes 14
  • Earliest
    J:84908 Lagos-Quintana M, et al., New microRNAs from mouse and human. RNA. 2003 Feb;9(2):175-9
  • Latest
    J:352041 Ye S, et al., DNA hypermethylation-induced miR-182 silence targets BCL2 and HOXA9 to facilitate the self-renewal of leukemia stem cell, accelerate acute myeloid leukemia progression, and determine the sensitivity of BCL2 inhibitor venetoclax. Theranostics. 2023;13(1):77-94
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory