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Mir196a-1 Gene Detail
Summary
  • Symbol
    Mir196a-1
  • Name
    microRNA 196a-1
  • Synonyms
    Mirn196, Mirn196a-1, mmu-mir-196a-1
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676860
    NCBI Gene: 387191
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:96155990-96156091 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 59.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    84 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676860
 miRNA gene Chr11:96155990-96156091 (+)
129S1/SvImJ MGP_129S1SvImJ_G0007863
 miRNA gene Chr11:98572524-98572625 (+)
A/J MGP_AJ_G0007856
 miRNA gene Chr11:94549811-94549912 (+)
AKR/J MGP_AKRJ_G0007831
 miRNA gene Chr11:97465164-97465265 (+)
BALB/cJ MGP_BALBcJ_G0007835
 miRNA gene Chr11:95045367-95045468 (+)
C3H/HeJ MGP_C3HHeJ_G0007781
 miRNA gene Chr11:97606636-97606737 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008014
 miRNA gene Chr11:101652050-101652151 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007155
 miRNA gene Chr11:92036319-92036420 (+)
CAST/EiJ MGP_CASTEiJ_G0007675
 miRNA gene Chr11:98425538-98425639 (+)
CBA/J MGP_CBAJ_G0007752
 miRNA gene Chr11:105816379-105816480 (+)
DBA/2J MGP_DBA2J_G0007787
 miRNA gene Chr11:94117026-94117127 (+)
FVB/NJ MGP_FVBNJ_G0007806
 miRNA gene Chr11:93596120-93596221 (+)
LP/J MGP_LPJ_G0007865
 miRNA gene Chr11:99112718-99112819 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007776
 miRNA gene Chr11:105814011-105814112 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008010
 miRNA gene Chr11:97781304-97781405 (+)
PWK/PhJ MGP_PWKPhJ_G0007602
 miRNA gene Chr11:95067358-95067459 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007497
 miRNA gene Chr11:97507028-97507129 (+)
WSB/EiJ MGP_WSBEiJ_G0007742
 miRNA gene Chr11:97667514-97667615 (+)



Homology
more
  • Human Ortholog
    MIR196A1, microRNA 196a-1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR196A1, microRNA 196a-1
  • Synonyms
    mir-196a-1, MIRN196-1, MIRN196A1
  • Links
    NCBI Gene ID: 406972

  • Chr Location
    chr17:48632490-48632559 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted deletion are viable with no observed pathologies.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    9
  • Literature Summary
    11
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      24
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 387191 NCBI Gene Model | MGI Sequence Detail 102 C57BL/6J ±  kb
    transcript NR_029721 RefSeq | MGI Sequence Detail 102 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 3
      Other 3
    Other Database
    Links
    less
    miRBase MI0000552
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 11
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
    • Latest
      J:317804 Hauswirth GM, et al., Breaking constraint of mammalian axial formulae. Nat Commun. 2022 Jan 11;13(1):243
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory