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Mir206 Gene Detail
Summary
  • Symbol
    Mir206
  • Name
    microRNA 206
  • Synonyms
    Mirn206, mmu-mir-206
Location &
Maps
more
  • Sequence Map
    Chr1:20749234-20749306 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 6.41 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    141 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676881
 miRNA gene Chr1:20749234-20749306 (+)
129S1/SvImJ MGP_129S1SvImJ_G0007596
 miRNA gene Chr1:18293274-18293346 (+)
A/J MGP_AJ_G0007593
 miRNA gene Chr1:18078709-18078781 (+)
AKR/J MGP_AKRJ_G0007565
 miRNA gene Chr1:18104991-18105063 (+)
BALB/cJ MGP_BALBcJ_G0007567
 miRNA gene Chr1:17767102-17767174 (+)
C3H/HeJ MGP_C3HHeJ_G0007514
 miRNA gene Chr1:18143790-18143862 (+)
C57BL/6NJ MGP_C57BL6NJ_G0007742
 miRNA gene Chr1:19166528-19166600 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0006920
 miRNA gene Chr1:16230167-16230239 (+)
CAST/EiJ MGP_CASTEiJ_G0007414
 miRNA gene Chr1:18234121-18234193 (+)
CBA/J MGP_CBAJ_G0007489
 miRNA gene Chr1:19598261-19598333 (+)
DBA/2J MGP_DBA2J_G0007522
 miRNA gene Chr1:17578101-17578173 (+)
FVB/NJ MGP_FVBNJ_G0007538
 miRNA gene Chr1:17344882-17344954 (+)
LP/J MGP_LPJ_G0007604
 miRNA gene Chr1:18522400-18522472 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007512
 miRNA gene Chr1:20553330-20553402 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0007743
 miRNA gene Chr1:18094406-18094478 (+)
PWK/PhJ MGP_PWKPhJ_G0007347
 miRNA gene Chr1:17328061-17328133 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007252
 miRNA gene Chr1:18189794-18189866 (+)
WSB/EiJ MGP_WSBEiJ_G0007478
 miRNA gene Chr1:18023010-18023082 (+)



Homology
more
  • Human Ortholog
    MIR206, microRNA 206
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR206, microRNA 206
  • Synonyms
    mir-206, MIRN206, miRNA206
  • Links
    NCBI Gene ID: 406989

  • Chr Location
    chr6:52144349-52144434 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human MIR206 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display abnormal motor nerve terminal sprouting.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    797
  • Tissues
    37
  • Literature Summary
    18
Sequences &
Gene Models
less
  • All Sequences
    25
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 387202 NCBI Gene Model | MGI Sequence Detail 73 C57BL/6J ±  kb
transcript NR_029593 RefSeq | MGI Sequence Detail 73 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 8
    Primer pair 1
    Other 7
Other Database
Links
less
miRBase MI0000249
References
more
  • Summaries
    All 60
    Developmental Gene Expression 18
    Gene Ontology 4
    Phenotypes 14
  • Earliest
    J:84908 Lagos-Quintana M, et al., New microRNAs from mouse and human. RNA. 2003 Feb;9(2):175-9
  • Latest
    J:328212 Klockner I, et al., Control of CRK-RAC1 activity by the miR-1/206/133 miRNA family is essential for neuromuscular junction function. Nat Commun. 2022 Jun 8;13(1):3180
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory