About   Help   FAQ
Mir210 Gene Detail
Summary
  • Symbol
    Mir210
  • Name
    microRNA 210
  • Synonyms
    Mirn210, mmu-mir-210
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676886
    NCBI Gene: 387206
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:140801297-140801406 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 86.52 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    76 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676886
 miRNA gene Chr7:140801297-140801406 (-)
129S1/SvImJ MGP_129S1SvImJ_G0009070
 miRNA gene Chr7:146398968-146399077 (-)
A/J MGP_AJ_G0009053
 miRNA gene Chr7:142211977-142212086 (-)
AKR/J MGP_AKRJ_G0009043
 miRNA gene Chr7:146132260-146132369 (-)
BALB/cJ MGP_BALBcJ_G0009039
 miRNA gene Chr7:141952712-141952821 (-)
C3H/HeJ MGP_C3HHeJ_G0008977
 miRNA gene Chr7:145888083-145888192 (-)
C57BL/6NJ MGP_C57BL6NJ_G0009278
 miRNA gene Chr7:151750571-151750680 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0008156
 miRNA gene Chr7:143421973-143422082 (-)
CAST/EiJ MGP_CASTEiJ_G0008812
 miRNA gene Chr7:138196808-138196917 (-)
CBA/J MGP_CBAJ_G0008948
 miRNA gene Chr7:156873602-156873711 (-)
DBA/2J MGP_DBA2J_G0008977
 miRNA gene Chr7:140159520-140159629 (-)
FVB/NJ MGP_FVBNJ_G0008996
 miRNA gene Chr7:140072769-140072878 (-)
LP/J MGP_LPJ_G0009072
 miRNA gene Chr7:147893865-147893974 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0008961
 miRNA gene Chr7:157541625-157541734 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0009247
 miRNA gene Chr7:145109104-145109213 (-)
PWK/PhJ MGP_PWKPhJ_G0008742
 miRNA gene Chr7:133440001-133440110 (-)
SPRET/EiJ MGP_SPRETEiJ_G0008583
 miRNA gene Chr7:131936501-131936610 (-)
WSB/EiJ MGP_WSBEiJ_G0008908
 miRNA gene Chr7:146057504-146057613 (-)



Homology
more
  • Human Ortholog
    MIR210, microRNA 210
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR210, microRNA 210
  • Synonyms
    mir-210, MIRN210
  • Links
    NCBI Gene ID: 406992

  • Chr Location
    chr11:568089-568198 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 4 alleles in 4 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for one targeted knock-out allele exhibit increased anti-nuclear antigen antibody level and decreased germinal center B cell number. Homozygous KO also leads to a male-specific decrease in nephron number.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    943
  • Tissues
    53
  • Literature Summary
    14
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      24
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 387206 NCBI Gene Model | MGI Sequence Detail 110 C57BL/6J ±  kb
    transcript NR_029793 RefSeq | MGI Sequence Detail 110 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 9
      Primer pair 6
      Other 3
    Other Database
    Links
    less
    miRBase MI0000695
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 14
      Gene Ontology 3
      Phenotypes 14
    • Earliest
      J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
    • Latest
      J:348548 Song R, et al., MicroRNA-210 Controls Mitochondrial Metabolism and Protects Heart Function in Myocardial Infarction. Circulation. 2022 Apr 12;145(15):1140-1153
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory