Mir212 MGI Mouse Gene Detail - MGI:2676888

Symbol

Mir212
Name

microRNA 212
Synonyms

Mirn212, mmu-mir-212

Feature Type

miRNA gene
IDs

MGI:2676888
NCBI Gene: 387208
Member of

Mirc19 cluster
Alliance

gene page

Sequence Map

Chr11:75064214-75064304 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 45.76 cM
Mapping Data

1 experiment

SNPs within 2kb

59 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2676888	miRNA gene	Chr11:75064214-75064304 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0007839	miRNA gene	Chr11:75904999-75905089 (+)
A/J	MGP_AJ_G0007834	miRNA gene	Chr11:73085944-73086034 (+)
AKR/J	MGP_AKRJ_G0007809	miRNA gene	Chr11:75300844-75300934 (+)
BALB/cJ	MGP_BALBcJ_G0007812	miRNA gene	Chr11:73456631-73456721 (+)
C3H/HeJ	MGP_C3HHeJ_G0007759	miRNA gene	Chr11:75313956-75314046 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0007990	miRNA gene	Chr11:78279843-78279933 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007134	miRNA gene	Chr11:70102464-70102554 (+)
CAST/EiJ	MGP_CASTEiJ_G0007652	miRNA gene	Chr11:75702256-75702346 (+)
CBA/J	MGP_CBAJ_G0007730	miRNA gene	Chr11:81717020-81717110 (+)
DBA/2J	MGP_DBA2J_G0007765	miRNA gene	Chr11:72691916-72692006 (+)
FVB/NJ	MGP_FVBNJ_G0007783	miRNA gene	Chr11:72253226-72253316 (+)
LP/J	MGP_LPJ_G0007843	miRNA gene	Chr11:76497800-76497890 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0007753	miRNA gene	Chr11:82303282-82303372 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0007987	miRNA gene	Chr11:75486530-75486620 (+)
PWK/PhJ	MGP_PWKPhJ_G0007580	miRNA gene	Chr11:73388239-73388329 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0007475	miRNA gene	Chr11:75057602-75057692 (+)
WSB/EiJ	MGP_WSBEiJ_G0007720	miRNA gene	Chr11:75305514-75305604 (+)

Human Ortholog

MIR212, microRNA 212

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR212, microRNA 212
Synonyms

mir-212, MIRN212
Links

HGNC:31589

NCBI Gene ID: 406994
Chr Location

chr17:2050271-2050380 (-) GRCh38

MGI Vertebrate Homology

Mir212 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR212
Gene Tree

Mir212

Diseases

1 with human MIR212 associations

				Human Disease	Mouse Models
				hepatocellular carcinoma IDs hepatocellular carcinoma DOID:684 DOID:5005 EFO:0000182 ICD10CM:C22.0 MESH:D006528 NCI:C3099 OMIM:114550 ORDO:88673 UMLS_CUI:C2239176

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

9 phenotype references

All Mutations and Alleles

3
Chemically induced (other)

1
Targeted

2
Genomic Mutations

3 involving Mir212
Find Mice (IMSR)

0 strains or lines available

Mice homozygous for an allele lacking both Mir212 and Mir132 exhibit disrupted cortical synaptic transmission and plasticity. Mice homozygous for another knock-out allele exhibit abnormal mammary gland development (see Mirc19).

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All GO Annotations

2
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
Literature Summary

2

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

24
RefSeq

1

Ensembl

ENSMUSG00000065590 (Evidence)
NCBI Gene

387208

Representative Sequences				Length	Strain/Species	Flank
	genomic	387208	NCBI Gene Model \| MGI Sequence Detail	91	C57BL/6J	± kb
	transcript	NR_029794	RefSeq \| MGI Sequence Detail	91	C57BL/6

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All nucleic 1

Other 1

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miRBase

MI0000696

Summaries

All 40

Developmental Gene Expression 2

Gene Ontology 1

Phenotypes 9
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:357960 Stojanovic T, et al., Age-Dependent and Pathway-Specific Bimodal Action of Nicotine on Synaptic Plasticity in the Hippocampus of Mice Lacking the miR-132/212 Genes. Cells. 2022 Jan 13;11(2)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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