About   Help   FAQ
Mir216a Gene Detail
Summary
  • Symbol
    Mir216a
  • Name
    microRNA 216a
  • Synonyms
    Mirn216, Mirn216a, mmu-mir-216a
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676892
    NCBI Gene: 387212
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr11:28707012-28707083 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 16.23 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    97 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676892
 miRNA gene Chr11:28707012-28707083 (+)
129S1/SvImJ MGP_129S1SvImJ_G0007790
 miRNA gene Chr11:26742494-26742565 (+)
A/J MGP_AJ_G0007786
 miRNA gene Chr11:25775240-25775311 (+)
AKR/J MGP_AKRJ_G0007760
 miRNA gene Chr11:26594836-26594907 (+)
BALB/cJ MGP_BALBcJ_G0007763
 miRNA gene Chr11:25932097-25932168 (+)
C3H/HeJ MGP_C3HHeJ_G0007710
 miRNA gene Chr11:26534886-26534957 (+)
C57BL/6NJ MGP_C57BL6NJ_G0007941
 miRNA gene Chr11:27725544-27725615 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007089
 miRNA gene Chr11:24446162-24446233 (+)
CAST/EiJ MGP_CASTEiJ_G0007605
 miRNA gene Chr11:26578072-26578143 (+)
CBA/J MGP_CBAJ_G0007682
 miRNA gene Chr11:28988246-28988317 (+)
DBA/2J MGP_DBA2J_G0007717
 miRNA gene Chr11:25623395-25623466 (+)
FVB/NJ MGP_FVBNJ_G0007734
 miRNA gene Chr11:25428858-25428929 (+)
LP/J MGP_LPJ_G0007794
 miRNA gene Chr11:27003773-27003844 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007705
 miRNA gene Chr11:30006943-30007014 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0007939
 miRNA gene Chr11:26734503-26734574 (+)
PWK/PhJ MGP_PWKPhJ_G0007534
 miRNA gene Chr11:25728741-25728812 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007431
 miRNA gene Chr11:26417654-26417725 (+)
WSB/EiJ MGP_WSBEiJ_G0007671
 miRNA gene Chr11:26409130-26409201 (+)



Homology
more
  • Human Ortholog
    MIR216A, microRNA 216a
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR216A, microRNA 216a
  • Synonyms
    mir-216, MIR216, mir-216a, MIRN216, MIRN216A, miRNA216
  • Links
    NCBI Gene ID: 406998

  • Chr Location
    chr2:55988950-55989059 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from multigenic genotypes
    6 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Targeted
    1
  • Genomic Mutations
    1 involving Mir216a
  • Find Mice (IMSR)
    1 strains or lines available
Mice homozygous for a null allele exhibit pancreatic acinar-to-ductal metaplasia in vitro and increased susceptibility to induced pancreatitis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    6
  • Literature Summary
    5
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 387212 NCBI Gene Model | MGI Sequence Detail 72 C57BL/6J ±  kb
transcript NR_029797 RefSeq | MGI Sequence Detail 72 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 3
    Primer pair 1
    Other 2
Other Database
Links
less
miRBase MI0000699
References
more
  • Summaries
    All 19
    Developmental Gene Expression 5
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:320867 Erener S, et al., Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice. Cell Rep Med. 2021 Nov 16;2(11):100434
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory