Mir23b MGI Mouse Gene Detail - MGI:2676898

Symbol

Mir23b
Name

microRNA 23b
Synonyms

Mirn23b, mmu-mir-23b

Feature Type

miRNA gene
IDs

MGI:2676898
NCBI Gene: 387217
Member of

Mirc22 cluster
Alliance

gene page

Sequence Map

Chr13:63448298-63448371 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 32.80 cM
Mapping Data

1 experiment

SNPs within 2kb

88 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2676898	miRNA gene	Chr13:63448298-63448371 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0008077	miRNA gene	Chr13:63260577-63260650 (+)
A/J	MGP_AJ_G0008067	miRNA gene	Chr13:60958743-60958816 (+)
AKR/J	MGP_AKRJ_G0008046	miRNA gene	Chr13:63000878-63000951 (+)
BALB/cJ	MGP_BALBcJ_G0008050	miRNA gene	Chr13:61387175-61387248 (+)
C3H/HeJ	MGP_C3HHeJ_G0007993	miRNA gene	Chr13:62533093-62533166 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0008235	miRNA gene	Chr13:65321327-65321400 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007338	miRNA gene	Chr13:58632886-58632959 (+)
CAST/EiJ	MGP_CASTEiJ_G0007876	miRNA gene	Chr13:62536081-62536154 (+)
CBA/J	MGP_CBAJ_G0007962	miRNA gene	Chr13:67842048-67842121 (+)
DBA/2J	MGP_DBA2J_G0007996	miRNA gene	Chr13:60801667-60801740 (+)
FVB/NJ	MGP_FVBNJ_G0008018	miRNA gene	Chr13:59919000-59919073 (+)
LP/J	MGP_LPJ_G0008079	miRNA gene	Chr13:63537387-63537460 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0007988	miRNA gene	Chr13:66815257-66815330 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0008233	miRNA gene	Chr13:62305516-62305589 (+)
PWK/PhJ	MGP_PWKPhJ_G0007797	miRNA gene	Chr13:60359981-60360054 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0007692	miRNA gene	Chr13:60460827-60460900 (+)
WSB/EiJ	MGP_WSBEiJ_G0007948	miRNA gene	Chr13:62795727-62795800 (+)

Human Ortholog

MIR23B, microRNA 23b

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR23B, microRNA 23b
Synonyms

hsa-mir-23b, mir-23b, MIRN23B, miRNA23B
Links

HGNC:31606

NCBI Gene ID: 407011
Chr Location

chr9:95085208-95085304 (+) GRCh38

MGI Vertebrate Homology

Mir23b stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR23B
Gene Tree

Mir23b

Diseases

2 with human MIR23B associations

				Human Disease	Mouse Models
				hepatocellular carcinoma IDs hepatocellular carcinoma DOID:684 DOID:5005 EFO:0000182 ICD10CM:C22.0 MESH:D006528 NCI:C3099 OMIM:114550 ORDO:88673 UMLS_CUI:C2239176
				ovarian carcinoma IDs ovarian carcinoma DOID:4001 EFO:0001075 UMLS_CUI:C0677886

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
8 phenotype references

All Mutations and Alleles

5
Chemically induced (other)

1
Endonuclease-mediated

2
Targeted

2
Genomic Mutations

3 involving Mir23b
Find Mice (IMSR)

4 strains or lines available

Mice homozygous for a targeted deletion are viable with no observed pathologies.

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All GO Annotations

9
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

791
Tissues

56
Literature Summary

16

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

23
RefSeq

1

Ensembl

ENSMUSG00000065599 (Evidence)
NCBI Gene

387217

Representative Sequences				Length	Strain/Species	Flank
	genomic	387217	NCBI Gene Model \| MGI Sequence Detail	74	C57BL/6J	± kb
	transcript	NR_029530	RefSeq \| MGI Sequence Detail	74	C57BL/6

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All nucleic 8

Primer pair 2

Other 6

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miRBase

MI0000141

Summaries

All 45

Developmental Gene Expression 16

Gene Ontology 6

Phenotypes 8
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:357928 Piasecka A, et al., MBNL splicing factors regulate the microtranscriptome of skeletal muscles. Nucleic Acids Res. 2024 Oct 28;52(19):12055-12073

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24