Mir27b MGI Mouse Gene Detail - MGI:2676903

Symbol

Mir27b
Name

microRNA 27b
Synonyms

Mirn27b, mmu-mir-27b

Feature Type

miRNA gene
IDs

MGI:2676903
NCBI Gene: 387221
Member of

Mirc22 cluster
Alliance

gene page

Sequence Map

Chr13:63448526-63448598 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 32.80 cM
Mapping Data

1 experiment

SNPs within 2kb

89 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2676903	miRNA gene	Chr13:63448526-63448598 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0008078	miRNA gene	Chr13:63260805-63260877 (+)
A/J	MGP_AJ_G0008068	miRNA gene	Chr13:60958971-60959043 (+)
AKR/J	MGP_AKRJ_G0008047	miRNA gene	Chr13:63001106-63001178 (+)
BALB/cJ	MGP_BALBcJ_G0008051	miRNA gene	Chr13:61387403-61387475 (+)
C3H/HeJ	MGP_C3HHeJ_G0007994	miRNA gene	Chr13:62533321-62533393 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0008236	miRNA gene	Chr13:65321555-65321627 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007339	miRNA gene	Chr13:58633114-58633186 (+)
CAST/EiJ	MGP_CASTEiJ_G0007877	miRNA gene	Chr13:62536309-62536381 (+)
CBA/J	MGP_CBAJ_G0007963	miRNA gene	Chr13:67842276-67842348 (+)
DBA/2J	MGP_DBA2J_G0007997	miRNA gene	Chr13:60801895-60801967 (+)
FVB/NJ	MGP_FVBNJ_G0008019	miRNA gene	Chr13:59919228-59919300 (+)
LP/J	MGP_LPJ_G0008080	miRNA gene	Chr13:63537615-63537687 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0007989	miRNA gene	Chr13:66815485-66815557 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0008234	miRNA gene	Chr13:62305744-62305816 (+)
PWK/PhJ	MGP_PWKPhJ_G0007798	miRNA gene	Chr13:60360209-60360281 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0007693	miRNA gene	Chr13:60461055-60461127 (+)
WSB/EiJ	MGP_WSBEiJ_G0007949	miRNA gene	Chr13:62795955-62796027 (+)

Human Ortholog

MIR27B, microRNA 27b

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR27B, microRNA 27b
Synonyms

MIR-27b, MIRN27B, miRNA27B
Links

HGNC:31614

NCBI Gene ID: 407019
Chr Location

chr9:95085445-95085541 (+) GRCh38

MGI Vertebrate Homology

Mir27b stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR27B
Gene Tree

Mir27b

Diseases

1 with human MIR27B associations

				Human Disease	Mouse Models
				stomach cancer IDs stomach cancer DOID:10534 DOID:10539 DOID:10542 DOID:10543 DOID:4713 ICD10CM:C16 ICD10CM:C16.2 ICD10CM:C16.5 ICD10CM:C16.6 ICD9CM:151 ICD9CM:151.4 ICD9CM:151.5 ICD9CM:151.6 ICD9CM:151.9 MESH:D013274 NCI:C3387 NCI:C9331 OMIM:613659 UMLS_CUI:C0024623 UMLS_CUI:C0038356 UMLS_CUI:C0153421 UMLS_CUI:C0153422 UMLS_CUI:C0153423

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

5 phenotype references

All Mutations and Alleles

3
Chemically induced (other)

1
Endonuclease-mediated

2
Genomic Mutations

3 involving Mir27b
Find Mice (IMSR)

2 strains or lines available

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All GO Annotations

11
GO References

8

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

761
Tissues

39
Literature Summary

18

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

23
RefSeq

1

Ensembl

ENSMUSG00000065475 (Evidence)
NCBI Gene

387221

Representative Sequences				Length	Strain/Species	Flank
	genomic	387221	NCBI Gene Model \| MGI Sequence Detail	73	C57BL/6J	± kb
	transcript	NR_029531	RefSeq \| MGI Sequence Detail	73	C57BL/6

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All nucleic 8

Primer pair 3

Other 5

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miRBase

MI0000142

Summaries

All 51

Developmental Gene Expression 18

Gene Ontology 8

Phenotypes 5
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:332900 Tang Y, et al., Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis. Cell Rep. 2023 Jan 5;42(1):111948

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/05/2024 MGI 6.24