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Mir30c-1 Gene Detail
Summary
  • Symbol
    Mir30c-1
  • Name
    microRNA 30c-1
  • Synonyms
    Mirn30c, Mirn30c-1, mmu-mir-30c-1
Location &
Maps
more
  • Sequence Map
    Chr4:120626731-120626819 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 56.52 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    42 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676909
 miRNA gene Chr4:120626731-120626819 (-)
129S1/SvImJ MGP_129S1SvImJ_G0008749
 miRNA gene Chr4:122051397-122051485 (-)
A/J MGP_AJ_G0008733
 miRNA gene Chr4:117247127-117247215 (-)
AKR/J MGP_AKRJ_G0008725
 miRNA gene Chr4:119818367-119818455 (-)
BALB/cJ MGP_BALBcJ_G0008723
 miRNA gene Chr4:117856121-117856209 (-)
C3H/HeJ MGP_C3HHeJ_G0008663
 miRNA gene Chr4:121351025-121351113 (-)
C57BL/6NJ MGP_C57BL6NJ_G0008942
 miRNA gene Chr4:126657231-126657319 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0007890
 miRNA gene Chr4:111301228-111301316 (-)
CAST/EiJ MGP_CASTEiJ_G0008505
 miRNA gene Chr4:118722349-118722437 (-)
CBA/J MGP_CBAJ_G0008629
 miRNA gene Chr4:130096443-130096531 (-)
DBA/2J MGP_DBA2J_G0008659
 miRNA gene Chr4:117822593-117822681 (-)
FVB/NJ MGP_FVBNJ_G0008680
 miRNA gene Chr4:116346268-116346356 (-)
LP/J MGP_LPJ_G0008754
 miRNA gene Chr4:122181082-122181170 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0008645
 miRNA gene Chr4:134913036-134913124 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0008923
 miRNA gene Chr4:120887414-120887502 (-)
PWK/PhJ MGP_PWKPhJ_G0008434
 miRNA gene Chr4:114764932-114765020 (-)
SPRET/EiJ MGP_SPRETEiJ_G0008286
 miRNA gene Chr4:117324671-117324759 (-)
WSB/EiJ MGP_WSBEiJ_G0008602
 miRNA gene Chr4:120906899-120906987 (-)



Homology
more
  • Human Ortholog
    MIR30C1, microRNA 30c-1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR30C1, microRNA 30c-1
  • Synonyms
    mir-30c-1, MIRN30C1
  • Links
    NCBI Gene ID: 407031

  • Chr Location
    chr1:40757284-40757372 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 3 alleles in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted deletion are viable with no observed pathologies.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    737
  • Tissues
    18
  • Literature Summary
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      24
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 387227 NCBI Gene Model | MGI Sequence Detail 89 C57BL/6J ±  kb
    transcript NR_029716 RefSeq | MGI Sequence Detail 89 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 6
      Primer pair 3
      Other 3
    Other Database
    Links
    less
    miRBase MI0000547
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 10
      Gene Ontology 5
      Phenotypes 11
    • Earliest
      J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
    • Latest
      J:294427 McCann JV, et al., Endothelial miR-30c suppresses tumor growth via inhibition of TGF-beta-induced Serpine1. J Clin Invest. 2019 Mar 11;129(4):1654-1670
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory