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Tas2r143 Gene Detail
Summary
  • Symbol
    Tas2r143
  • Name
    taste receptor, type 2, member 143
  • Synonyms
    mt2r36, Tas2r43
  • Feature Type
    protein coding gene
  • IDs
    MGI:2681310
    NCBI Gene: 387514
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr6:42377172-42378053 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 20.70 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    93 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2681310
protein coding gene Chr6:42377172-42378053 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030650
protein coding gene Chr6:40917822-40918703 (+)
A/J MGP_AJ_G0030623
protein coding gene Chr6:39130591-39131472 (+)
AKR/J MGP_AKRJ_G0030548
protein coding gene Chr6:40393422-40394303 (+)
BALB/cJ MGP_BALBcJ_G0030633
protein coding gene Chr6:39387203-39388084 (+)
C3H/HeJ MGP_C3HHeJ_G0030346
protein coding gene Chr6:40430140-40431021 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031087
protein coding gene Chr6:41940429-41941310 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028294
protein coding gene Chr6:37012321-37013202 (+)
CAST/EiJ MGP_CASTEiJ_G0029750
protein coding gene Chr6:40263846-40264727 (+)
CBA/J MGP_CBAJ_G0030322
protein coding gene Chr6:43637735-43638616 (+)
DBA/2J MGP_DBA2J_G0030466
protein coding gene Chr6:38980091-38980972 (+)
FVB/NJ MGP_FVBNJ_G0030422
protein coding gene Chr6:38728511-38729392 (+)
LP/J MGP_LPJ_G0030554
protein coding gene Chr6:40880512-40881393 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030456
protein coding gene Chr6:45913356-45914237 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031117
protein coding gene Chr6:40368511-40369392 (+)
PWK/PhJ MGP_PWKPhJ_G0029462
protein coding gene Chr6:38544090-38544971 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029298
protein coding gene Chr6:39928819-39929700 (+)
WSB/EiJ MGP_WSBEiJ_G0029826
protein coding gene Chr6:40357553-40358433 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 387514 NCBI Gene Model | MGI Sequence Detail 882 C57BL/6J ±  kb
transcript NM_001001452 RefSeq | MGI Sequence Detail 882 C57BL/6  
polypeptide Q7TQB9 UniProt | EBI | MGI Sequence Detail 293 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 17
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:83522 Shi P, et al., Adaptive diversification of bitter taste receptor genes in Mammalian evolution. Mol Biol Evol. 2003 May;20(5):805-14
  • Latest
    J:334098 Kobayashi D, et al., Tas2R signaling enhances mouse neutrophil migration via a ROCK-dependent pathway. Front Immunol. 2022;13:973880

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory