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Serpinb3d Gene Detail
Summary
  • Symbol
    Serpinb3d
  • Name
    serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D
  • Feature Type
    protein coding gene
  • IDs
    MGI:2683295
    NCBI Gene: 394252
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:107005893-107011210 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 50.34 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    264 from dbSNP Build 142
  • Strain Annotations
    8
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2683295
 protein coding gene Chr1:107005893-107011236 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J MGP_AKRJ_G0016322
 protein coding gene Chr1:108335136-108341209 (-)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0015727
 protein coding gene Chr1:107672896-107717557 (-)
CBA/J MGP_CBAJ_G0016117
 protein coding gene Chr1:117452840-117545984 (-)
DBA/2J MGP_DBA2J_G0016222
 protein coding gene Chr1:104505128-104513027 (-)
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0016816
 protein coding gene Chr1:108409344-108416256 (-)
PWK/PhJ MGP_PWKPhJ_G0015514
 protein coding gene Chr1:103771897-103789784 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015302
 protein coding gene Chr1:107246804-107255300 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    SERPINB3, serpin family B member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SERPINB3, serpin family B member 3
  • Synonyms
    HsT1196, SCC, SCCA-1, SCCA1, SCCA-PD, SSCA1, T4-A
  • Links
    NCBI Gene ID: 6317
    neXtProt AC: NX_P29508
    UniProt: P29508

  • Chr Location
    18q21.33; chr18:63655197-63661893 (-)  GRCh38
  • Human Ortholog
    SERPINB4, serpin family B member 4
  • Synonyms
    LEUPIN, PI11, SCCA1, SCCA-2, SCCA2
  • Links
    NCBI Gene ID: 6318
    neXtProt AC: NX_P48594
    UniProt: P48594

  • Chr Location
    18q21.33; chr18:63637259-63644256 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 394252 NCBI Gene Model | MGI Sequence Detail 5318 C57BL/6J ±  kb
    transcript NM_201376 RefSeq | MGI Sequence Detail 1164 BALB/c  
    polypeptide NP_958764 RefSeq | MGI Sequence Detail 387 BALB/c  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      Genomic 5
      cDNA 3

      Microarray probesets 1
    References
    more
    • Summaries
      All 24
      Gene Ontology 2
      Phenotypes 10
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory