Pom121l2 MGI Mouse Gene Detail - MGI:2684870 - POM121 transmembrane nucleoporin like 2

Symbol

Pom121l2
Name

POM121 transmembrane nucleoporin like 2
Synonyms

LOC195236

Feature Type

protein coding gene
IDs

MGI:2684870
NCBI Gene: 195236
Alliance

gene page
Transcription Start Sites

4 TSS

Sequence Map

Chr13:22165364-22172904 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 8.11 cM
Mapping Data

1 experiment

SNPs within 2kb

278 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2684870	protein coding gene	Chr13:22165351-22172904 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0020305	protein coding gene	Chr13:19300760-19308236 (+)
A/J	MGP_AJ_G0020263	protein coding gene	Chr13:18853008-18862468 (+)
AKR/J	MGP_AKRJ_G0020235	protein coding gene	Chr13:19184915-19192385 (+)
BALB/cJ	MGP_BALBcJ_G0020251	protein coding gene	Chr13:18903202-18910686 (+)
C3H/HeJ	MGP_C3HHeJ_G0020059	protein coding gene	Chr13:19277608-19285115 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0020690	protein coding gene	Chr13:19980070-19987600 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018295	protein coding gene	Chr13:17145911-17153577 (+)
CAST/EiJ	MGP_CASTEiJ_G0019582	protein coding gene	Chr13:19073191-19081861 (+)
CBA/J	MGP_CBAJ_G0020013	protein coding gene	Chr13:20636640-20644184 (+)
DBA/2J	MGP_DBA2J_G0020138	protein coding gene	Chr13:18494585-18502042 (+)
FVB/NJ	MGP_FVBNJ_G0020123	protein coding gene	Chr13:18148619-18151904 (+)
LP/J	MGP_LPJ_G0020208	protein coding gene	Chr13:19526799-19536532 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020153	protein coding gene	Chr13:21036739-21045348 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020722	protein coding gene	Chr13:18984554-18992699 (+)
PWK/PhJ	MGP_PWKPhJ_G0019338	protein coding gene	Chr13:18513902-18522074 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0019150	protein coding gene	Chr13:17970085-17979913 (+)
WSB/EiJ	MGP_WSBEiJ_G0019643	protein coding gene	Chr13:19103060-19111382 (+)

Human Ortholog

POM121L2, POM121 transmembrane nucleoporin like 2

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

POM121L2, POM121 transmembrane nucleoporin like 2
Synonyms

POM121-L, POM121L
Links

HGNC:13973

NCBI Gene ID: 94026

neXtProt AC: NX_Q96KW2

UniProt: Q96KW2
Chr Location

6p22.1; chr6:27285903-27312273 (-) GRCh38

MGI Vertebrate Homology

Pom121l2 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: POM121L2
Gene Tree

Pom121l2

less

Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
13 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

7
Chemically induced (other)

1
Endonuclease-mediated

1
Gene trapped

3
Radiation induced

1
Targeted

1
Genomic Mutations

2 involving Pom121l2
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

50 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

less

All GO Annotations

5
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

8

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

less

All Sequences

32
RefSeq

5
UniProt

2
CCDS

CCDS49216.1, CCDS49217.1

Ensembl

ENSMUSG00000016982 (Evidence)
NCBI Gene

195236

			Length	Strain/Species	Flank
genomic	ENSMUSG00000016982	Ensembl Gene Model \| MGI Sequence Detail	7541	C57BL/6J	± kb
transcript	ENSMUST00000017126	Ensembl \| MGI Sequence Detail	2960	Not Applicable
polypeptide	ENSMUSP00000017126	Ensembl \| MGI Sequence Detail	972	Not Applicable

less

UniProt

2 Sequences
Protein Ontology

PR:000013014 POM121-like protein 2

(term hierarchy)
InterPro Domains

IPR026054 Nuclear pore complex protein

less

All nucleic 8

cDNA 8

Microarray probesets 1

Summaries

All 29

Gene Ontology 1

Phenotypes 13
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Pom121l2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr118809	Chr13:22165360-22165374 (+)	3 bp
Tssr118810	Chr13:22165388-22165393 (+)	27 bp
Tssr118811	Chr13:22165622-22165674 (+)	284 bp
Tssr118812	Chr13:22165687-22165692 (+)	326 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24