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Ciart Gene Detail
Summary
  • Symbol
    Ciart
  • Name
    circadian associated repressor of transcription
  • Synonyms
    Gm129, LOC229599
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684975
    NCBI Gene: 229599
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:95785815-95789563 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 41.42 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    114 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684975
 protein coding gene Chr3:95785812-95790012 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027597
 protein coding gene Chr3:96661549-96665306 (-)
A/J MGP_AJ_G0027556
 protein coding gene Chr3:93632056-93635658 (-)
AKR/J MGP_AKRJ_G0027523
 protein coding gene Chr3:95814959-95818713 (-)
BALB/cJ MGP_BALBcJ_G0027568
 protein coding gene Chr3:93412713-93416458 (-)
C3H/HeJ MGP_C3HHeJ_G0027301
 protein coding gene Chr3:96116068-96119822 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028016
 protein coding gene Chr3:100206079-100209827 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025356
 protein coding gene Chr3:89958841-89962445 (-)
CAST/EiJ MGP_CASTEiJ_G0026751
 protein coding gene Chr3:95393322-95396918 (-)
CBA/J MGP_CBAJ_G0027278
 protein coding gene Chr3:103873318-103877072 (-)
DBA/2J MGP_DBA2J_G0027417
 protein coding gene Chr3:92923319-92927067 (-)
FVB/NJ MGP_FVBNJ_G0027388
 protein coding gene Chr3:91001242-91005019 (-)
LP/J MGP_LPJ_G0027526
 protein coding gene Chr3:97973696-97977804 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027415
 protein coding gene Chr3:110001846-110005623 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028070
 protein coding gene Chr3:95463030-95467172 (-)
PWK/PhJ MGP_PWKPhJ_G0026479
 protein coding gene Chr3:92819404-92824397 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026300
 protein coding gene Chr3:93753944-93757687 (-)
WSB/EiJ MGP_WSBEiJ_G0026833
 protein coding gene Chr3:95854367-95858248 (-)



Homology
more
  • Human Ortholog
    CIART, circadian associated repressor of transcription
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CIART, circadian associated repressor of transcription
  • Synonyms
    C1orf51, CHRONO, GM129
  • Links
    NCBI Gene ID: 148523
    neXtProt AC: NX_Q8N365
    UniProt: Q8N365

  • Chr Location
    1q21.2; chr1:150282543-150287093 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 3 alleles in 3 genetic backgrounds
    1 phenotype from multigenic genotypes
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Null mutants have slightly prolonged expression of circadian genes
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038550 Ensembl Gene Model | MGI Sequence Detail 3749 C57BL/6J ±  kb
    transcript ENSMUST00000036418 Ensembl | MGI Sequence Detail 1398 Not Applicable  
    polypeptide ENSMUSP00000049308 Ensembl | MGI Sequence Detail 375 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • Protein Ontology
      PR:000059927 circadian-associated transcriptional repressor
      (term hierarchy)
    • InterPro Domains
      IPR031373 Circadian-associated transcriptional repressor
    • GlyGen
      Q3TQ03 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 3
    References
    more
    • Summaries
      All 38
      Diseases 1
      Gene Ontology 4
      Phenotypes 17
    • Earliest
      J:33331 Nishiguchi S, et al., A catalogue of genes in mouse embryonal carcinoma F9 cells identified with expressed sequence tags. J Biochem. 1996 Apr;119(4):749-67
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory