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Cym Gene Detail
Summary
  • Symbol
    Cym
  • Name
    chymosin
  • Synonyms
    Gm131, LOC229697
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684977
    NCBI Gene: 229697
  • Alliance
    gene page
  • Transcription Start Sites
    46 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:107118611-107129048 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 46.68 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    457 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684977
 protein coding gene Chr3:107118609-107129048 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027742
 protein coding gene Chr3:108689354-108699794 (-)
A/J MGP_AJ_G0027702
 protein coding gene Chr3:105247110-105257608 (-)
AKR/J MGP_AKRJ_G0027667
 protein coding gene Chr3:107818971-107829342 (-)
BALB/cJ MGP_BALBcJ_G0027714
 protein coding gene Chr3:104944132-104954527 (-)
C3H/HeJ MGP_C3HHeJ_G0027444
 protein coding gene Chr3:108159823-108170249 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028158
 protein coding gene Chr3:112768094-112778533 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025496
 protein coding gene Chr3:101408873-101419237 (-)
CAST/EiJ MGP_CASTEiJ_G0026900
 protein coding gene Chr3:107529257-107539696 (-)
CBA/J MGP_CBAJ_G0027419
 protein coding gene Chr3:116580067-116590509 (-)
DBA/2J MGP_DBA2J_G0027561
 protein coding gene Chr3:104448636-104459042 (-)
FVB/NJ MGP_FVBNJ_G0027529
 protein coding gene Chr3:102328512-102338950 (-)
LP/J MGP_LPJ_G0027668
 protein coding gene Chr3:110106062-110116490 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027559
 protein coding gene Chr3:122705506-122715897 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028213
 protein coding gene Chr3:107405353-107415801 (-)
PWK/PhJ MGP_PWKPhJ_G0026626
 protein coding gene Chr3:104174164-104184587 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026446
 protein coding gene Chr3:105542441-105553013 (-)
WSB/EiJ MGP_WSBEiJ_G0026980
 protein coding gene Chr3:107931704-107942207 (-)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Cym
  • Find Mice (IMSR)
    21 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    12
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 229697 NCBI Gene Model | MGI Sequence Detail 10438 C57BL/6J ±  kb
transcript NM_001111143 RefSeq | MGI Sequence Detail 1234 C57BL/6  
polypeptide NP_001104613 RefSeq | MGI Sequence Detail 379 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001461 Aspartic peptidase A1 family
    IPR001969 Aspartic peptidase, active site
    IPR021109 Aspartic peptidase domain superfamily
    IPR012848 Aspartic peptidase, N-terminal
    IPR033121 Peptidase family A1 domain
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:297081 Sayols S, et al., Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors. Development. 2020 Sep 15;147(18):dev188839
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory